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GenomicsDrug-induced cis-regulatory elements in human hepatocytes affect molecular phenotypes associated with drug efficacy and adverse reactions
Drug-induced cis-regulatory elements in human hepatocytes affect molecular phenotypes associated with drug efficacy and adverse reactions
PRJNA1135139 | ENA
UnknownHLA Association with Drug-Induced Adverse Reactions.
Not available
S-EPMC5733150 | biostudies-literature
ProteomicsEffects of cis-regulatory elements on proteome
Background Genomic variations contribute to the phenotypic diversity of individuals. A number of polymorphisms in protein-coding regions that alter drug efficacy or lead to adverse reactions have been characterized; however, noncoding regions that affect drug responses are largely overlooked, except...
ORGANISM(S): Homo sapiens (Human) 
2025-04-17 | PXD060446 | Pride
Human Dia Hepatocyte Lc-ms/ms 
UnknownSevere Cutaneous Adverse Reactions to Anti-tuberculosis Drugs in Korean Patients.
Not available
S-EPMC7840880 | biostudies-literature
TranscriptomicsTranscription profiling of human Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis patients blister cells from skin lesions reveals these consist of cytotoxic T cells annd NK cells
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis; (TEN) are life-threatening adverse drug reactions characterized; by massive epidermal necrosis, in which the specific danger; signals involved remain unclear. Here we show that blister; cells from skin lesions of SJS-TEN primarily consis...
ORGANISM(S): Homo sapiens 
2009-01-13 | E-GEOD-13727 | biostudies-arrayexpress
UnknownPharmacogenetics for severe adverse drug reactions induced by molecular-targeted therapy.
Not available
S-EPMC7540972 | biostudies-literature
UnknownDrug-induced cis-regulatory elements in human hepatocytes affect molecular phenotypes associated with adverse reactions.
Not available
S-EPMC12041347 | biostudies-literature
UnknownPharmacogenomics of adverse drug reactions.
Not available
S-EPMC3707028 | biostudies-literature
UnknownHLA-A*24:02 as a common risk factor for antiepileptic drug-induced cutaneous adverse reactions.
Not available
S-EPMC5467955 | biostudies-literature
UnknownSevere Cutaneous Adverse Reactions to Antiepileptic Drugs: A Nationwide Registry-Based Study in Korea.
Not available
S-EPMC6658409 | biostudies-literature
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