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GenomicsMicrobacterium sp. T-DSG1
Microbacterium sp. T-DSG1 Genome sequencing
PRJNA1446180 | ENA
ProteomicsEpidermal Stratification Requires Retromer-Mediated Desmoglein-1 Recycling
Sorting transmembrane cargo is essential for tissue development and homeostasis. However, mechanisms of intracellular trafficking in stratified epidermis are poorly understood. Here we identify an interaction between the retromer endosomal trafficking component, VPS35, and the desmosomal cadherin, D...
ORGANISM(S): Homo sapiens (Human) 
2023-07-24 | PXD036646 | Pride
Desmosome  keratinocyte  epidermal differentiation  skin disease  endosomal trafficking  retromer chaperone  vps35  sam syndrome  cadherin  dsg1  glut1  bioid 
UnknownA DSG1 Frameshift Variant in a Rottweiler Dog with Footpad Hyperkeratosis.
Not available
S-EPMC7230267 | biostudies-literature
UnknownDsg1 and Dsg3 Composition of Desmosomes Across Human Epidermis and Alterations in Pemphigus Vulgaris Patient Skin.
Not available
S-EPMC9196036 | biostudies-literature
UnknownNovel nonsense variants in SLURP1 and DSG1 cause palmoplantar keratoderma in Pakistani families.
Not available
S-EPMC6708247 | biostudies-literature
UnknownThe DSG1-AS1/miR-125b-5p/HMGA2 axis is associated with the formation of neutrophil extracellular traps in atopic dermatitis.
Not available
S-EPMC12706904 | biostudies-literature
TranscriptomicsTranslational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor III
Desmoglein 1 (Dsg1) is a cadherin restricted to stratified tissues of terrestrial vertebrates, which serve as essential physical and immune barriers. Dsg1 loss-of-function mutations in humans result in skin lesions, multiple allergies, and isolated patient keratinocytes exhibit increased pro-allergi...
ORGANISM(S): Homo sapiens 
2021-11-25 | GSE189096 | GEO
TranscriptomicsTranslational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor I
Desmoglein 1 (Dsg1) is a cadherin restricted to stratified tissues of terrestrial vertebrates, which serve as essential physical and immune barriers. Dsg1 loss-of-function mutations in humans result in skin lesions, multiple allergies, and isolated patient keratinocytes exhibit increased pro-allergi...
ORGANISM(S): Mus musculus 
2021-11-25 | GSE189094 | GEO
TranscriptomicsTranslational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor II
Desmoglein 1 (Dsg1) is a cadherin restricted to stratified tissues of terrestrial vertebrates, which serve as essential physical and immune barriers. Dsg1 loss-of-function mutations in humans result in skin lesions, multiple allergies, and isolated patient keratinocytes exhibit increased pro-allergi...
ORGANISM(S): Mus musculus 
2021-11-25 | GSE189095 | GEO
TranscriptomicsCrosstalk in Skin: Loss of Desmoglein 1 in Keratinocytes Inhibits BRAFV600E-induced Cellular Senescence in Human Melanocytes
Melanoma arises from transformation of melanocytes in the basal layer of the epidermis where they are surrounded by keratinocytes, with which they interact through cell contact and paracrine communication. Although research focuses on how the accumulation of oncogene and tumor suppressor gene mutati...
ORGANISM(S): Homo sapiens 
2024-11-18 | GSE255546 | GEO
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