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MetabolomicsFirst-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. Therapies to restore hepatocyte regeneration are lacking, making liver transplantation...

2024-09-23 | MTBLS9434 | MetaboLights
ProteomicsDual-Probe Activity-Based Protein Profiling Reveals Site-Specific Binding Dynamics of EGFR-Directed Drugs
Comparative, dose-dependent analysis of interactions between small molecule drugs and their targets, as well as off-targets, in complex proteomes is crucial for selecting optimal drug candidates. The affinity of small molecules for targeted proteins is largely dictated by interactions between amino ...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD045864 | Pride
Chemical proteomics  activity-based protein profiling  site-specific  concentration-dependent analysis  dual-probe comparison. 
UnknownProbing G-quadruplex topologies and recognition concurrently in real time and 3D using a dual-app nucleoside probe.
Not available
S-EPMC6614846 | biostudies-literature
UnknownFacile synthesis and evaluation of a dual-functioning furoyl probe for in-cell SHAPE.
Not available
S-EPMC6258071 | biostudies-literature
UnknownDual-labeled anti-GD2 targeted probe for intraoperative molecular imaging of neuroblastoma.
Not available
S-EPMC11476241 | biostudies-literature
UnknownDual-Probe Transcranial Full-Waveform Inversion: A Brain Phantom Feasibility Study.
Not available
S-EPMC7616382 | biostudies-literature
UnknownBLV-CoCoMo Dual qPCR Assay Targeting LTR Region for Quantifying Bovine Leukemia Virus: Comparison with Multiplex Real-Time qPCR Assay Targeting pol Region.
Not available
S-EPMC11677995 | biostudies-literature
TranscriptomicsComparison of cornea to the surface tissues, dermis and epidermis, in adult zebrafish
The gene expression profile of the adult zebrafish cornea was assessed in comparison to those from closely associated surface tissues: the dermis and epidermis. This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Danio rerio 
2015-02-19 | E-GEOD-24599 | biostudies-arrayexpress
UnknownCombined fiber probe for fluorescence lifetime and Raman spectroscopy.
Not available
S-EPMC4995092 | biostudies-literature
UnknownA benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency.
Not available
S-EPMC11863645 | biostudies-literature
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