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MetabolomicsElucidating dynamic anaerobe metabolism with HRMAS 13C NMR and genome-scale modeling
Not available
ORGANISM(S): Clostridioides difficile 
ST002433 | MetabolomicsWorkbench
MetabolomicsEcophysiological Study of Paraburkholderia sp. Strain 1N under Soil Solution Conditions: Dynamic Substrate Preferences and Characterization of Carbon Use Efficiency

We used time-resolved metabolic footprinting, an important technical approach used to monitor changes in extracellular compound concentrations during microbial growth, to study the order of substrate utilization (i.e., substrate preferences) and kinetics of a fast-growing soil isolate, Parabu...

2020-09-28 | MTBLS1692 | MetaboLights
MetabolomicsDynamic Changes and Clinical Significance of Gut Microbiota and Serum Metabolites in Breast Cancer Onset, Progression and Chemotherapy Intervention

Background: Breast cancer progression and treatment are increasingly linked to systemic metabolic and microbial alterations. Previous studies have identified distinct gut microbiome profiles and serum metabolite shifts in breast cancer patients compared to healthy individuals, yet longitudi...

2026-05-08 | MTBLS13634 | MetaboLights
ProteomicsElucidating Fibroblast Growth Factor-induced kinome dynamics using targeted mass spectrometry and dynamic modeling
Fibroblast growth factors (FGFs) are paracrine or endocrine signaling proteins that when activated by their ligands, can elicit a wide range of healthy and disease-related processes such as cell proliferation and the epithelial-to-mesenchymal transition (EMT). The detailed molecular pathway dynamics...
ORGANISM(S): Homo sapiens (Human) 
2023-07-02 | PXD038836 | Pride
Phosphoproteomics  kinase  targeted mass spectrometry  kinase dynamics  fibroblast growth factors  dynamic modeling  fibroblast growth factor receptor  breast cancer.  
ProteomicsElucidating Fibroblast Growth Factor-induced kinome dynamics using targeted mass spectrometry and dynamic modeling
Fibroblast growth factors (FGFs) are paracrine or endocrine signaling proteins that when activated by their ligands, can elicit a wide range of healthy and disease-related processes such as cell proliferation and the epithelial-to-mesenchymal transition (EMT). The detailed molecular pathway dynamics...
ORGANISM(S): Homo sapiens (Human) 
2023-07-02 | PXD038808 | Pride
Phosphoproteomics  kinase  targeted mass spectrometry  kinase dynamics  fibroblast growth factors  dynamic modeling  fibroblast growth factor receptor  breast cancer.  
ProteomicsElucidating Fibroblast Growth Factor-induced kinome dynamics using targeted mass spectrometry and dynamic modeling
Fibroblast growth factors (FGFs) are paracrine or endocrine signaling proteins that when activated by their ligands, can elicit a wide range of healthy and disease-related processes such as cell proliferation and the epithelial-to-mesenchymal transition (EMT). The detailed molecular pathway dynamics...
ORGANISM(S): Homo Sapiens 
PXD039005 | panorama
UnknownExplainable deep learning for tumor dynamic modeling and overall survival prediction using Neural-ODE.
Not available
S-EPMC10657412 | biostudies-literature
GenomicsDynamic analysis of gene expression and genome wide transcription factor binding during lineage-specification of multipotent progenitors [ChIP-seq].
We used the paradigmatic 'GATA-PU.1 axis’ to explore, at systems-level, dynamic relationships between transcription factor (TF) binding and global gene expression programs as multipotent cells differentiate. We combined global ChIPSeq of GATA1, GATA2 and PU.1 with expression profiling during differe...
ORGANISM(S): Mus musculus 
2013-10-17 | E-GEOD-50406 | biostudies-arrayexpress
TranscriptomicsDynamic analysis of gene expression and genome wide transcription factor binding during lineage-specification of multipotent progenitors [TC]
An expression time course experiment to investigate gene expression changes during differentiation of multipotential cells over two lineages using the model cell line FDCPmix differentiating towards erytroid and myeloid fates. We used the paradigmatic 'GATA-PU.1 axis’ to explore, at systems-level, d...
ORGANISM(S): Mus musculus 
2013-10-17 | E-GEOD-49987 | biostudies-arrayexpress
TranscriptomicsDynamic analysis of gene expression and genome wide transcription factor binding during lineage-specification of multipotent progenitors [HP]
FDCPmix cells were infected with Gata, Pu1 shRNAs and microarrayed 5 days after infecton as part of a study investigating the differentiation of a multipotential cell-line to erthroid and myeloid fates. We used the paradigmatic 'GATA-PU.1 axis’ to explore, at systems-level, dynamic relationships bet...
ORGANISM(S): Mus musculus 
2013-10-17 | E-GEOD-49989 | biostudies-arrayexpress
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