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MetabolomicsMulti-omic analysis of vaginal bacteria:host immune and metabolic interactions in early adverse pregnancy outcomes

Objective

To characterise the vaginal microbiota, mucosal metabolome and host immune response in early pregnancy and investigate its relationship with adverse pregnancy outcomes, including ectopic pregnancy, within the context of pregnancies of unknown location (PUL).

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2025-03-28 | MTBLS10098 | MetaboLights
ProteomicsProteome-defined changes in cellular pathways for decidua and trophoblast tissues associated with location and viability of early-stage pregnancy
A label-free proteome analysis comparing changes in protein profiles of decidualized endometria and trophoblasts among women with different pregnancy outcomes, specifically a viable intrauterine pregnancy (IUP), ectopic pregnancy (EP), or early pregnancy loss (EPL), that identify potential biomarker...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-12-16 | MSV000088572 | MassIVE
ProteomicsHuman salivary proteome to map biomarker for ectopic pregnancy
Explore the profile of salivary proteins with an attention during ectopic pregnancy adopting gel based protein mass spectrometry
ORGANISM(S): Homo sapiens (Human) 
2023-07-16 | PXD036633 | Pride
Human Ectopic Lc-msms Pregnancy Saliva 
MetabolomicsDiagnostic utility of clinicodemographic, biochemical and metabolite variables to identify viable pregnancies in a symptomatic cohort during early gestation.

Study question: Can a novel machine learning pipeline create predictive models that identify a composite biomarker to differentiate live normally sited pregnancies (LNSP) from non-viable pregnancies in women presenting with pain and/or bleeding in early gestation?

Summary answer: Serum met...

2025-08-14 | MTBLS6219 | MetaboLights
UnknownTerminology for describing normally sited and ectopic pregnancies on ultrasound: ESHRE recommendations for good practice.
Not available
S-EPMC7738750 | biostudies-literature
TranscriptomicsDifferential miRNA profiles of pregnancy tissue in ectopic pregnancies
Abstract Objective: To investigate the physiology of ectopic pregnancy by analyzing the miRNA profiles of the pregnancy tissue from both ectopic and control pregnancies (voluntary termination of pregnancy). Design: Research study. Setting: Academic research institute in collaboration with a universi...
ORGANISM(S): Homo sapiens 
2014-06-02 | E-GEOD-44731 | biostudies-arrayexpress
TranscriptomicsTubal ectopic pregnancy as a model to identify endometrial genes and signaling pathways important in decidualization and regulated by local trophoblast
Gestation-matched endometrium was collected from women with ectopic pregnancy (EP) (n=11) and intrauterine pregnancies (IUP) (n=13). RNA was extracted from the tissue. In addition, tissues were prepared for histological analysis for degree of decidualization. We compared a) the samples from EP that ...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-MTAB-680 | biostudies-arrayexpress
TranscriptomicsWhy nicotine is BAD for your Fallopian tube: an explanation for the association between smoking and ectopic pregnancy
Why nicotine is BAD for your Fallopian tube: an explanation for the association between smoking and ectopic pregnancy
ORGANISM(S): Homo sapiens 
2014-08-01 | E-MTAB-1290 | biostudies-arrayexpress
GenomicsHomo sapiens
Decidual transcriptome in ectopic pregnancy
PRJDB37600 | ENA
GenomicsDifferential miRNA profiles of pregnancy tissue in ectopic pregnancies
Abstract Objective: To investigate the physiology of ectopic pregnancy by analyzing the miRNA profiles of the pregnancy tissue from both ectopic and control pregnancies (voluntary termination of pregnancy). Design: Research study. Setting: Academic research institute in collaboration with a universi...
ORGANISM(S): Homo sapiens 
2014-06-02 | GSE44731 | GEO
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