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ProteomicsQuantitative phosphoproteomic analysis reveals the regulatory networks of elovl6 on lipid and glucose metabolism in zebrafish
Elongation of very long-chain fatty acids protein 6 (Elovl6) has been reported to be associated with clinical treatments of a variety of metabolic diseases. However, there is no systematic and comprehensive study to reveal the regulatory role of Elovl6 in the mRNA, protein and phosphorylation levels...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2020-05-27 | PXD017702 | Pride
Zebrafish  elovl6 knockout  transcriptomics  proteomics  phosphoproteomics  lipid/glucose metabolism 
GenomicsHepatic transcriptome profiling of liver-specific Elovl6 knockout mice fed a high-sucrose diet
Hepatic transcriptome profiling of liver-specific Elovl6 knockout mice fed a high-sucrose diet
PRJNA508938 | ENA
TranscriptomicsHepatic transcriptome profiling of liver-specific Elovl6 knockout mice fed a high-sucrose diet
Elovl6 is a member of mammalian fatty acid elongase that is responsible for converting C16 saturated and monounsaturated fatty acids into C18 species. To understand the role of Elovl6 in liver, we generated liver-specific Elovl6 knockout mice (Albumin-Cre;Elovl6 fl/fl C57BL/6J). The goal of this exp...
ORGANISM(S): Mus musculus 
2019-09-20 | GSE123494 | GEO
UnknownCrucial Role of Elovl6 in Chondrocyte Growth and Differentiation during Growth Plate Development in Mice.
Not available
S-EPMC4965081 | biostudies-literature
UnknownFPR2 Agonism Attenuates Restenosis by Mitigating Neointimal Hyperplasia via ELOVL6.
Not available
S-EPMC12413656 | biostudies-literature
UnknownThe Knockout of the ASIP Gene Altered the Lipid Composition in Bovine Mammary Epithelial Cells via the Expression of Genes in the Lipid Metabolism Pathway.
Not available
S-EPMC9179457 | biostudies-literature
TranscriptomicsIdentification of CD44 downstream target genes
CD44 expression has been shown to be enhanced in the liver and white adipose tissue (WAT) during obesity, suggesting a possible regulatory role for CD44 in metabolic syndrome. To study this hypothesis, we compared the gene expression profiles in liver and in WAT between WT and CD44 knockout (CD44KO)...
ORGANISM(S): Mus musculus 
2013-06-01 | E-GEOD-43104 | biostudies-arrayexpress
UnknownZebrafish cobll1a regulates lipid homeostasis via the RA signaling pathway.
Not available
S-EPMC11063382 | biostudies-literature
TranscriptomicsIdentification of CD44 downstream target genes
CD44 expression has been shown to be enhanced in the liver and white adipose tissue (WAT) during obesity, suggesting a possible regulatory role for CD44 in metabolic syndrome. To study this hypothesis, we compared the gene expression profiles in liver and in WAT between WT and CD44 knockout (CD44KO)...
ORGANISM(S): Mus musculus 
2013-06-01 | GSE43104 | GEO
UnknownKruppel-like factor KLF10 is a link between the circadian clock and metabolism in liver.
Not available
S-EPMC2876690 | biostudies-literature
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