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MetabolomicsInulin gel-mediated delivery of Clostridium butyricum spores protects against acute kidney injury via regulation of ER-mitochondria contacts
Acute kidney injury (AKI) progression is closely associated with gut microbiota dysbiosis. However, the detailed mechanism remains unclear. In this study, we found that patients with AKI had decreased beneficial bacteria and reduced butyric acid levels in the intestine. Furthermore, butyrate allevia...
2026-09-17 | MTBLS15607 | MetaboLights
GenomicsMitochondria-Rough-ER Contacts in The Liver Regulate Systemic Lipid Homeostasis
Mitochondria-Rough-ER Contacts in The Liver Regulate Systemic Lipid Homeostasis
PRJNA556401 | ENA
UnknownER-mitochondria contacts promote mitochondrial-derived compartment biogenesis.
Not available
S-EPMC7588143 | biostudies-literature
Unknownβ2-adrenergic receptor regulates ER-mitochondria contacts.
Not available
S-EPMC8563895 | biostudies-literature
GenomicsIncrease in ER-mitochondria contacts and mitochondrial fusion are hallmarks of mitochondrial activation during embryogenesis
Increase in ER-mitochondria contacts and mitochondrial fusion are hallmarks of mitochondrial activation during embryogenesis
PRJNA1111056 | ENA
UnknownLtc1 is an ER-localized sterol transporter and a component of ER-mitochondria and ER-vacuole contacts.
Not available
S-EPMC4442815 | biostudies-literature
ProteomicsRevisiting the relevance of the accumulation of apolipoprotein E (APOE) in mitochondria-associated ER membranes: Investi-gation of hepatic protein-protein interactions of APOE with LONP1, TOMM40 and VDAC1
Investigating the subcellular distribution and protein interaction of APOE and the modulation by cellular stress signals, we aimed to contribute to the elucidation of putative novel functions. We identified APOE as hepatic mitochondria-associated ER-membranes (MAM) protein, where it most likely inte...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055281 | Pride
Mitochondria-er contacts (merc) Mam Stress response Proteome analysis Subcellular distribution Liver Apoe4 
ProteomicsInfection-induced peripheral mitochondria fission drives ER encapsulations that rescue bioenergetics
During infection, viruses rely on altering organelle shape, location, and abundance to modulate cellular functions. The prevalent pathogen human cytomegalovirus (HCMV) induces mitochondria fragmentation while paradoxically promoting respiration. Using super-resolution and cryo-electron tomography, w...
ORGANISM(S): Homo sapiens (Human) 
2024-07-25 | PXD038330 | Pride
Hcmv Mitochondria Virus Ptpip51 
UnknownCalcium channel ITPR2 and mitochondria-ER contacts promote cellular senescence and aging.
Not available
S-EPMC7851384 | biostudies-literature
UnknownER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells.
Not available
S-EPMC5554545 | biostudies-literature
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