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UnknownERAL1 is associated with mitochondrial ribosome and elimination of ERAL1 leads to mitochondrial dysfunction and growth retardation.
Not available
S-EPMC2938226 | biostudies-literature
GenomicsmRNA-seq of wild-type or Eral1 deficient primary peritoneal macrophages (PMs) after sendai virus infection
mRNA-seq of wild-type or Eral1 deficient primary peritoneal macrophages (PMs) after sendai virus infection
PRJNA679557 | ENA
TranscriptomicsmRNA-seq of wild-type or Eral1 deficient primary peritoneal macrophages (PMs) after sendai virus infection
Analysis of mRNA-seq reveals how wild-type and Eral1 deficient peritoneal macrophages response to SeV infection
ORGANISM(S): Mus musculus 
2020-11-20 | GSE161809 | GEO
UnknownA homozygous missense mutation in ERAL1, encoding a mitochondrial rRNA chaperone, causes Perrault syndrome.
Not available
S-EPMC5965403 | biostudies-literature
UnknownCLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels.
Not available
S-EPMC5283601 | biostudies-literature
UnknownHuman ERAL1 is a mitochondrial RNA chaperone involved in the assembly of the 28S small mitochondrial ribosomal subunit.
Not available
S-EPMC2995420 | biostudies-literature
ProteomicsThe mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling
MAVS-Turbo ID IP in HEK293T cells treated with or without SeV
ORGANISM(S): Homo Sapiens 
2020-12-08 | PXD023002 |
UnknownGlobal Proteome of LonP1+/- Mouse Embryonal Fibroblasts Reveals Impact on Respiratory Chain, but No Interdependence between Eral1 and Mitoribosomes.
Not available
S-EPMC6770551 | biostudies-literature
ProteomicsClpP-deletion causes azoospermia, with meiosis-I delay and insufficient biosynthesis of spermatid factors, due to mitochondrial dysfunction with accumulation of Perrault proteins ERAL1, PEO1, and HARS2.
Human Perrault syndrome (PRLTS) is defined by autosomal recessive inheritance with primary ovarian insufficiency and early hearing loss. Most PRLTS disease proteins modulate mitochondrial transcription or translation. Among the genetic causes are ClpP mutations, which trigger also complete azoosperm...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD033388 | Pride
Meiosis-i  zygotene-pachytene  homologous recombination  h3k9ac  acetyl-tubulin  twinkle helicase  rmnd1  trna /rrna processing  cgas-sting signaling 
UnknownCLPP Depletion Causes Diplotene Arrest; Underlying Testis Mitochondrial Dysfunction Occurs with Accumulation of Perrault Proteins ERAL1, PEO1, and HARS2.
Not available
S-EPMC9818230 | biostudies-literature
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