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MetabolomicsCharacterization of Blood Metabolites and the Uterine Microbiota in Estrus Simmental Cattle

Accurate oestrus detection is critical for optimizing reproductive efficiency in beef cattle, yet the underlying metabolic and microbial mechanisms remain poorly understood, particularly in Simmental cattle. To address this gap, we employed an integrated metabolomics and microbiome approach ...

2025-07-20 | MTBLS12755 | MetaboLights
MetabolomicsSerum Metabolomics Reveals Stage-Dependent Metabolic Transitions During CIDR-PGF2alpha-Induced Estrus in Kazak Ewes
This study investigated serum metabolic transitions during CIDR-PGF2alpha-induced estrus synchronization in Kazak ewes using UHPLC-MS/MS untargeted metabolomics. Eighteen Kazak ewes were assigned to three reproductive stages: luteal phase (LP), luteolysis phase (LDP), and estrus phase (OES), with si...
2026-08-09 | MTBLS15117 | MetaboLights
ProteomicsQuantitative proteomic analysis and verification identify global protein profiling dynamics in pig saliva during the estrus cycle
The current estrus detection method is generally time-consuming and has low accuracy. As such, a deeper understanding of the physiological processes during the estrus cycle accelerates the development of estrus detection efficiency and accuracy. This study used label-free acquisition mass spectromet...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-09-15 | PXD043141 | Pride
Sow  estrus detection  saliva  quantitative proteomics  differentially expressed proteins  reproduction efficiency 
TranscriptomicsEstrus Synchronization and Ovarian Hyper Stimulation Treatments Have Negligible Effects on Cumulus Oocyte Complexes Gene Expression: Induction of Ovulation Causes Major Expression Changes
The effects of exogenous hormones used for estrus synchronization, and ovarian hyper stimulation on cumulus oocyte complexes (COCs) gene expression in sexually mature rats were determined using microarrays. Gene expression in COCs collected from GnRH (Gtrt), GnRH+eCG (G+Etrt), and GnRH+eCG+hCG (G+E+...
ORGANISM(S): Rattus norvegicus 
2013-02-01 | E-GEOD-41836 | biostudies-arrayexpress
TranscriptomicsEvidence for an early endometrial response to pregnancy in cattle: both dependent upon and independent of interferon tau
The aims of this study were to 1) identify the earliest transcriptional response of the bovine endometrium to the presence of the conceptus (using RNAseq), 2) investigate if these genes are regulated by interferon tau (IFNT) in vivo, and 3) determine if they are predictive of the pregnancy status of...
ORGANISM(S): Bos taurus 
2014-04-01 | E-GEOD-56392 | biostudies-arrayexpress
UnknownUrinary metabolite signatures as predictive biomarkers for estrus detection in water buffaloes: a proton-NMR based study.
Not available
S-EPMC12915391 | biostudies-literature
UnknownEstrus Detection in a Dairy Herd Using an Electronic Nose by Direct Sampling on the Perineal Region.
Not available
S-EPMC9786671 | biostudies-literature
UnknownAdvancing 3Rs: The Mouse Estrus Detector (MED) as a Low-Stress, Painless, and Efficient Tool for Estrus Determination in Mice.
Not available
S-EPMC11395264 | biostudies-literature
UnknownComparative Proteome Profiling of Saliva Between Estrus and Non-Estrus Stages by Employing Label-Free Quantitation (LFQ) and Tandem Mass Tag (TMT)-LC-MS/MS Analysis: An Approach for Estrus Biomarker Identification in Bubalus bubalis.
Not available
S-EPMC9217162 | biostudies-literature
UnknownUrinary Cell-Free miR-99a-5p as a Potential Biomarker for Estrus Detection in Buffalo.
Not available
S-EPMC8165190 | biostudies-literature
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