Sort   by:  
 Page size 
Extracellular matrix proteomic profiling Mass spectrometry characterization illustrated a reprogrammed proteome in response to matrix stiffness, including a core subset of 84 ECM-specific proteins, including various ECM regulators and tissue-associated ECM-related proteins. Further, we observe remod...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
The objective of this study was to investigate the effects of rosiglitazone (Avandia) on gene expression in neonatal rat ventricular myocytes. Myocytes were exposed to rosiglitazone ex vivo. The two factors examined in the experiment were drug exposure (r
ORGANISM(S): Rattus norvegicus 
To identify genes implicated in metastatic colonization of the liver in colorectal cancer, we collected pairs of primary tumors and hepatic metastases before chemotherapy in 13 patients. We compared mRNA expression in the pairs of patients to identify genes deregulated during metastatic evolution. W...
ORGANISM(S): Homo sapiens 
Human amniotic epithelial cell-derived extracellular vesicles (hAEC-EVs) have shown therapeutic potential in corneal injury repair; however, the underlying molecular mechanisms, particularly those related to extracellular matrix (ECM) remodeling, remain incompletely understood.
ORGANISM(S): Oryctolagus Cuniculus 
2026-03-11 | PXD075526 |
To identify genes implicated in metastatic colonization of the liver in colorectal cancer, we collected pairs of primary tumors and hepatic metastases before chemotherapy in 13 patients. We compared mRNA expression in the pairs of patients to identify genes deregulated during metastatic evolution. W...
ORGANISM(S): Homo sapiens 
The extracellular matrix (ECM) is fundamental to cellular and tissue structural integrity and provides mechanical cues to initiate diverse biological functions1. The quality and quantity of ECM determines tissue stiffness and controls gene expression, cell fate, and cell cycle progression in various...
ORGANISM(S): Rattus Rattus (black Rat) 
Calcific aortic valve disease (CAVD) is the most common valvular heart disease in older adults, but no medical therapy is currently able to halt or reverse its progression, partly because the molecular mechanisms of valve remodeling remain incompletely understood. Here, we aimed to dissect the extra...
ORGANISM(S): Homo sapiens (Human) 
2026-05-29 | PXD073246 | Pride
Extracellular matrix (ECM) remodeling is strongly linked to Alzheimer’s disease (AD) risk, but its functions are not fully understood. Here, we found that medial prefrontal cortex (mPFC) injection with chondroitinase ABC (ChABC) to remodel ECM reverses short-term memory loss and reduces Aβ depositio...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD046784 | Pride
Extracellular matrix remodeling regulates glucose metabolism through TXNIP destabilization
Multiscale Analysis of Extracellular Matrix Remodeling in the Failing Heart
Sort   by:  
 Page size