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ProteomicsFAM134B oligomerization drives ER membrane scission for ER-phagy
ER degradation by selective autophagy (ER-phagy) is crucial for ER homeostasis. However, it remains unclear how ER scission is regulated for subsequent autophagosomal sequestration and lysosomal degradation. Here, we show that oligomer formation of FAM134B (also referred to as reticulophagy regulato...
ORGANISM(S): Homo sapiens (Human) 
2020-01-09 | PXD016661 | Pride
Er-phagy  fam134b oligomerization  membrane fragmentation  er stress  camk2b 
ProteomicsThe ER-phagy receptor FAM134B is targeted by Salmonella Typhimurium to promote infection
Macroautophagy/autophagy is a key catabolic-recycling pathway that can selectively target damaged organelles or invading pathogens for degradation. The selective autophagic degradation of the endoplasmic reticulum (hereafter referred to as ER-phagy) is a homeostatic mechanism, controlling ER size, t...
ORGANISM(S): Homo sapiens (Human) Salmonella enterica subsp. enterica 
2025-05-07 | PXD061148 | Pride
Ap-ms sopf fam134b 
UnknownFAM134B oligomerization drives endoplasmic reticulum membrane scission for ER-phagy.
Not available
S-EPMC7049798 | biostudies-literature
ProteomicsIntracellular lipopolysaccharide regulates ER remodeling upon bacterial infection
The remodeling of endoplasmic reticulum (ER) is finely regulated by selective autophagy, known as ER-phagy. However, whether Gram-negative bacteria, which are known to manipulate the host membranous system, regulate ER-phagy remains elusive. We find that bacterial lipopolysaccharide (LPS) released u...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD053709 | Pride
Lipopolysaccharide Fam134b Er-phagy 
UnknownThe ER-phagy receptor FAM134B is targeted by Salmonella Typhimurium to promote infection.
Not available
S-EPMC11937434 | biostudies-literature
UnknownFAM134B oligomerization drives endoplasmic reticulum membrane scission for ER-phagy
Not available
S-SCDT-EMBOJ-2019-102608 | biostudies-other
UnknownPRRSV non-structural protein 5 inhibits antiviral innate immunity by degrading multiple proteins of RLR signaling pathway through FAM134B-mediated ER-phagy.
Not available
S-EPMC11495150 | biostudies-literature
UnknownUbiquitination regulates ER-phagy and remodelling of endoplasmic reticulum.
Not available
S-EPMC10247366 | biostudies-literature
UnknownFull length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy.
Not available
S-EPMC5517149 | biostudies-literature
UnknownUVRAG cooperates with cargo receptors to assemble the ER-phagy site
Not available
S-SCDT-10_15252-EMBJ_2023113625 | biostudies-other
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