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MetabolomicsFlavonoid-targeted metabolomic analysis.

Flavonoids, one of the major groups of root exudates, are active molecules mediating plant-PGPR interactions. Flavonoids can alleviate nutrient deficiencies and drought stress to maintain normal plant growth. Here, We used flavonoid targeted metabolomic analysis to profile flavonoid components an...

2025-12-14 | MTBLS13507 | MetaboLights
MetabolomicsComparative analysis of flavonoid metabolites from different parts of Hemerocallis citrina

Hemerocallis citrina Baroni is a traditional medical and edible plant with various health benefits. Currently, many phytochemical analyses have been performed and various biological constituents have been extracted from H. citrina. Flavonoid compounds are a kind of important bioactive components....

2023-10-02 | MTBLS7978 | MetaboLights
MetabolomicsFlavonoid Biosynthesis Is Likely More Susceptible to Elevation and Tree Age Than Other Branch Pathways Involved in Phenylpropanoid Biosynthesis in Ginkgo Leaves
Ginkgo leaves are always resources for flavonoids pharmaceutical industry. However, the effect of the elevation and tree age changes on flavonoid biosynthesis have not been detailly explored in Ginkgo leaves. In addition, whether these environmental pressures have similar effects on the biosynthesis...
2020-12-14 | MTBLS962 | MetaboLights
MetabolomicsHigh-level de novo synthesis of medical plant derived flavonoid glycosides
Pichia pastoris is a widely used eukaryotic host for recombinant protein expression in biopharmaceutical and biomanufacturing, offering advantages such as broad carbon source utilization, high cell density, a mature fermentation process, and genomic stability. Recent advances in genetic editing and ...
2025-08-22 | MTBLS12177 | MetaboLights
MetabolomicsUrinary metabolomic profiling to identify biomarkers of a flavonoid-rich and flavonoid-poor fruits and vegetables diet in adults: the FLAVURS trial
The present study aims to investigate the dose dependent effects of consuming diets enriched in flavonoid-rich and flavonoid-poor fruits and vegetables on the urine metabolome of adults who had a ≥1.5 fold increased risk of cardiovascular diseases. A single-blind, dose-dependent, parallel randomized...
2017-01-19 | MTBLS198 | MetaboLights
MetabolomicsTranscriptome and Metabolome Analyses Reveal Differences in Terpenoid and Flavonoid Biosynthesis in Cryptomeria fortunei Needles Across Different Seasons

Cryptomeria fortunei (Chinese cedar) has outstanding medicinal value due to its abundant flavonoid and terpenoid contents. The metabolite contents of C. fortunei needles differ across different seasons. However, the biosynthetic mechanism of these differentially synthesized meta...

2022-08-12 | MTBLS4099 | MetaboLights
MetabolomicsRegulation of flavonoid accumulation during tuber development of 'Tiegun' yam (Dioscorea polystachya Turcz.)

‘Tiegun’ yam (Dioscorea polystachya Turcz.) is regarded as a medicinal and edible crop with extremely health-preserving values. However, the types and accumulation of bioactive substances in ‘Tiegun’ are incompletely elucidated. We firstly explored the bioactive substance accumulation across the...

2026-01-16 | MTBLS13686 | MetaboLights
MetabolomicsSingle-cell Transcriptomics and Time-series Metabolite Profiling Reveal the Spatiotemporal Regulation of Flavonoid Biosynthesis Genes and Phytohormone Homeostasis by PAP1 in Arabidopsis
Understanding the spatiotemporal regulation of specialized metabolism in plants is critical for advancing both basic plant biology and biotechnological applications. In this study, we utilized single-cell RNA sequencing (scRNA-seq) and time-series metabolite profiling to investigate the regulation o...
2025-05-27 | MTBLS12459 | MetaboLights
MetabolomicsA Multi-Omics Analysis of Glycine max Leaves Reveals Alteration in Flavonoid and Isoflavonoid Metabolism Upon Ethylene and Abscisic Acid Treatment
Phytohormones are central to plant growth and development. Despite the advancement in our knowledge of hormone signaling, downstream targets, and their interactions upon hormones action remain largely fragmented, especially at the protein and metabolite levels. With an aim to get new insight into th...
2018-09-20 | MTBLS531 | MetaboLights
MetabolomicsDefective cytokinin signaling reprograms lipid and flavonoid gene-to-metabolite networks to mitigate high salinity in Arabidopsis

Cytokinin (CK) in plants regulates both developmental processes and adaptation to environmental stress. Arabidopsis histidine phosphotransfer ahp2,3,5 and type-B response regulator arr1,10,12 triple mutants are almost completely defective in CK signaling, and the ahp2,3,5

2021-11-25 | MTBLS2532 | MetaboLights
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