Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of human monocyte derived dendritric cells matured with Galectin-1 or LPS vs controls
Human monocyte derived dendritic cells matured via galectin-1 or LPS. Experiment Overall Design: 4 conditions with 3 replicates of each include control or intreated immature MDDCS, galectin-1 treated MDDCs, LPS treated MDDCs, and vehicle control MDDCs. (each replicate is from a distinct DONOR). Dend...
ORGANISM(S): Homo sapiens 
2007-10-26 | E-GEOD-4984 | biostudies-arrayexpress
TranscriptomicsGalectin-1 couples glycobiology to inflammation in osteoarthritis through the activation of an NF-κB-regulated gene network
Osteoarthritis is a degenerative joint disease that ranks among the leading causes of pain, adult disability, shortening of working life, and socioeconomic costs worldwide. The mechanisms underlying osteoarthritis pathogenesis are yet to be fully elucidated, thus limiting current disease management ...
ORGANISM(S): Homo sapiens 
2016-03-01 | E-GEOD-68760 | biostudies-arrayexpress
ProteomicsSILAC-based proteomic profiling of the human colon cancer cell line LS 180 in response to exogenous galectin-4
Galectins constitute a family of ß-galactoside binding proteins that translate sugar-encoded signals of cell surface glycoconjugates into biological effects. The expression pattern of different human galectins changes during tissue development and is altered at sites of inflammation and tumor. Galec...
ORGANISM(S): Homo sapiens (Human) 
2016-12-23 | PXD003489 | Pride
Human Lc-msms Colon cancer Silac Ls 180 Galectin-4 
ProteomicsEndoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners
Endoglin is a 180-kDa glycoprotein receptor primarily expressed by the vascular endothelium and involved in cardiovascular disease and cancer. Heterozygous mutations in the endoglin gene (ENG) cause Hereditary Hemorrhagic Telangiectasia type 1, a vascular disease that present with nose and gastroint...
ORGANISM(S): Mesocricetus auratus (Golden hamster) Homo sapiens (Human) 
2019-09-25 | PXD015402 | Pride
Endothelial cells  endoglin  tgf-β  bmp  hht  cancer  preeclampsia  trim family  galectin family  protein-protein interactions 
GenomicsInnate immune function of galectin-1 as a DAMP
Innate immune function of galectin-1 as a DAMP
PRJNA591290 | ENA
UnknownGalectin Family Members: Emerging Novel Targets for Lymphoma Therapy?
Not available
S-EPMC9168125 | biostudies-literature
TranscriptomicsInnate immune function of galectin-1 as a DAMP
Galectin-1 is a prototype member of the galectin family of b-galactoside-binding proteins with several immunoregulatory activities (Sundblad et al., 2017). Although this lectin exerts extracellular activities by cross-linking cell surface glycoconjugates, the mechanisms and molecular machinery invol...
ORGANISM(S): Mus musculus 
2020-10-29 | GSE140892 | GEO
UnknownA Synthetic Tetramer of Galectin-1 and Galectin-3 Amplifies Pro-apoptotic Signaling by Integrating the Activity of Both Galectins.
Not available
S-EPMC6966408 | biostudies-literature
UnknownA brief history of galectin evolution.
Not available
S-EPMC10343441 | biostudies-literature
UnknownIdentification of VPS13C as a Galectin-12-Binding Protein That Regulates Galectin-12 Protein Stability and Adipogenesis.
Not available
S-EPMC4830523 | biostudies-literature
Sort   by:  
 Page size