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Galectins constitute a family of ß-galactoside binding proteins that translate sugar-encoded signals of cell surface glycoconjugates into biological effects. The expression pattern of different human galectins changes during tissue development and is altered at sites of inflammation and tumor. Galec...
ORGANISM(S): Homo sapiens (Human) 
2016-12-23 | PXD003489 | Pride
Expression data of primary osteoarthritic chondrocytes treated with Galectin-4
Prostate cancer (PCa) causes significant mortality among men worldwide. Galectin-4 plays an important roles in regulatiog cancer metastasis and high level of galectin-4 correlated with poor survival in subpopulation of PCa patients. To further understand the galectin-4-mediated signature and develop...
ORGANISM(S): Homo sapiens 
2018-06-30 | GSE100301 | GEO
The severity of osteoarthritis is linked to elevated levels of galectins. Here, the aim of the study was to evaluate the role of Galectin-4 in osteoarthritic cartilage.
ORGANISM(S): Homo sapiens 
2022-02-23 | GSE183531 | GEO
Extracellular galectin 4 drives immune evasion and promotes T-cell apoptosis in pancreatic cancer [RNA-Seq]
Genome-wide analysis of galectin-4 mediated gene signature in PCa
Extracellular galectin 4 drives immune evasion and promotes T-cell apoptosis in pancreatic cancer [scRNA-Seq]
In order to systematically explore Galectin-4 function in CRC we established a CRC cell line where Gal4 expression can be regulated via doxycycline (dox)-inducible expression of a single copy wildtype LGALS4 transgene generated by recombinase-mediated cassette exchange (RMCE). Using this model and a...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD032902 | Pride
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