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Ten physically active subjects underwent two cycling exercise trials. In the first, aerobic capacity (VO2max) was determined and the second was a 45 min submaximal exercise test. Urine samples were collected separately the day before (day 1), the day of (day 2), and the day after (day 3) the submaxi...
2017-05-16 | MTBLS306 | MetaboLights

While the risk factors for Type 2 diabetes (T2DM) are known, early predictive markers of transition from normal to a prediabetes state are unidentified. We studied the basal metabolism and metabolic response to a mixed-meal challenge in 110 healthy subjects in the age group of 18 to 40 years (Mal...

2019-03-14 | MTBLS743 | MetaboLights

To evaluate the therapeutic potential of Lactiplantibacillus plantarum Probio87 in adults with functional constipation (FC), a randomized, double-blind, placebo-controlled trial was conducted. A total of 101 adults meeting the Rome IV diagnostic criteria for FC were enrolled. All participants rec...

2025-10-09 | MTBLS13105 | MetaboLights
Human blood plasma is a complex which communicates with most parts of the body and reflects changes in the state of the organism, therefore identifying age-related biomarkers can help to predict and monitor age-related physiological decline and diseases, as well as to find new treatments for disease...
ORGANISM(S): Homo sapiens (Human) 
2020-10-19 | PXD016199 | Pride
In this study, we provided a comprehensive lifespan characterization of urine metabolomics in a cohort of 348 healthy children and 315 adults aged 1 to 70 years using liquid chromatography coupled with high resolution mass spectrometry.
ORGANISM(S): Homo Sapiens 
2022-06-06 | PXD034390 |
Ultra-rare biallelic ATG7 variants were recently reported in five families presenting with neurodevelopmental disorders. Two adult female siblings (P1 and P2) from one family carried compound heterozygous loss-of-function variants (c.1975C>T [p.Arg659]; c.2080-2A>G, 39,40NM_006395.2), resulting in u...
2026-09-30 | MTBLS15856 | MetaboLights
Bronchoalveolar lavage of healthy human adults
Comparative genomic hybridisation of 20 Staphylococcus aureus isolates from healthy adults.
ORGANISM(S): Staphylococcus aureus 
vastus lateralis biopsies were obtained from healthy subjects, either young adults (20-29 yr old) or older (65-75 yr old)
ORGANISM(S): Homo sapiens 
T cell dysfunction is an important feature of many chronic viral infections. In particular, it was shown that PD-1 regulates T cell dysfunction during chronic LCMV infection in mice and PD-1 high cells exhibit an intense exhausted gene signature. These findings were extended to human chronic infecti...
ORGANISM(S): Homo sapiens 
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