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MetabolomicsLipidomic profiling of Scd1- and Scd2-deficient C2C12 cells during brown adipogenic differentiation with oleic acid supplementation
This study investigated the lipidomic remodeling of Scd1- and Scd2-deficient C2C12 cells during brown adipogenic differentiation. Scd1 or Scd2 knockout cells and corresponding control cells were induced to undergo brown adipocyte-like differentiation for 96 h. To evaluate whether exogenous monounsat...
2026-06-23 | MTBLS14692 | MetaboLights
GenomicsBrassica napus high oleic acid vs. low oleic acid
Brassica napus high oleic acid vs. low oleic acid
PRJNA492174 | ENA
MetabolomicsDendrobium officinale Polysaccharide Ameliorates High-Fat Diet-Induced Hepatic Lipid Metabolic Disorder via the SIRT6/PGC-1α Signaling Axis
Aims: This study aims to explore the potential therapeutic effect of Dendrobium officinale polysaccharide (DOP) on non-alcoholic fatty liver disease (NAFLD) induced by high-fat diet (HFD), and to elucidate the underlying mechanism involving the SIRT6/PGC-1α signaling axis and the regulation of the g...
2026-05-25 | MTBLS14575 | MetaboLights
ProteomicsAn immature high-oleic acid near-isogenic line of rapeseed
To identify differentially expressed proteins in a high-oleic acid rapeseed line, self-bred seeds (20 to 35 days after pollination) of a high- and a low-oleic acid rapeseed near-isogenic line (oleic acid contents of 81.4% and 56.2%, respectively) were used as raw materials for iTRAQ (isobaric tags f...
ORGANISM(S): Brassica napus (Rape) 
2022-02-23 | PXD006491 | Pride
Isobaric tags for relative and absolute quantification  high oleic  fatty acid  rapeseed 
TranscriptomicsBrassica napus high oleic acid vs. low oleic acid
Compared to ordinary rapeseed, high-oleic acid rapeseed has higher levels of monounsaturated fatty acids and lower levels of saturated fatty acid and polyunsaturated fatty acids, and thus is of high nutritional and health value. In addition, high-oleic acid rapeseed oil imparts cardiovascular protec...
ORGANISM(S): Brassica napus 
2018-09-20 | GSE120223 | GEO
MetabolomicsSacha inchi oil alleviates gut microbiota dysbiosis and improves hepatic lipid dysmetabolism in high-fat diet-fed rats
Dietary ω-3 polyunsaturated fatty acids (PUFAs) are beneficial for humans against the development of hyperlipidaemia, but the underlying mechanisms are still poorly understood. Here, we demonstrated that oral consumption of sacha inchi oil, which is rich in α-linolenic acid, alleviated dyslipidemia,...
2022-02-21 | MTBLS1225 | MetaboLights
TranscriptomicsGrowth competition experiment on the Yeast Homozygous Diploid Deletion Pool to investigate which ORFs conferred an advantage/disadvantage when growing on both standard and high concentration of oleic acid
The combination of genetic analysis and genome-wide expression profiles make Saccharomyces cerevisiae the cradle of Systems Biology. The way S. cerevisiae uses carbon sources has long been a landmark for studies concerning cellular responses to environmental conditions. S. cerevisiae conserves the e...
ORGANISM(S): Saccharomyces cerevisiae 
2012-04-25 | E-GEOD-21620 | biostudies-arrayexpress
MetabolomicsMetabolome of NAFLD in high fat diet mouse model
Not available
ORGANISM(S): Mus musculus 
ST001680 | MetabolomicsWorkbench
TranscriptomicsAdipose tissue nutrigenomic study in Iberian pigs with dietary intervention of oleic acid supplementation
We studied the influence of the oleic acid content of the diet on adipose tissue transcriptome. Iberian pigs were fed a standard (C) or a high oleic sunflower oil enriched (HO) diet. Transcriptome analyses were performed in adipose tissue samples (inner layer) obtained at slaughter (110 kg live weig...
ORGANISM(S): Sus scrofa 
2013-06-14 | E-GEOD-47941 | biostudies-arrayexpress
GenomicsComparative transcriptomic analyses of high and low oleic acid content sunflower (Helianthus annuus L.) seed development
Comparative transcriptomic analyses of high and low oleic acid content sunflower (Helianthus annuus L.) seed development
PRJNA688902 | ENA
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