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ProteomicsNAT10-mediated ac4C-modification exacerbates ferroptosis by stabilizing HMOX1 in Deep vein thrombosis
In our study, we aimed to identify the pathways and genes closely related to DVT. Through proteomic analysis, we found that the ferroptosis signaling pathway showed differential expression, and we also discovered that NAT10 (a key acetyltransferase modified by ac4C) was significantly overexpressed i...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-26 | PXD067933 | Pride
Deep venous thrombosis  nat10  ac4c  hmox1  ferroptosis 
TranscriptomicsTranscriptional profile of overexpression of HMOX1 or/and pimozide-treated cancer cell lines MIA PaCa-2, HCT 116, SK-OV-3, and AGS
DRD2 antagonists are commonly used clinically for the treatment of psychiatric disorders. This study aimed to explore the antitumor effects of DRD2 antagonists on a variety of tumor entities. A DRD2 antagonist, pimozide, exhibited antitumor effects in pancreatic, colorectal, ovarian, and gastric can...
ORGANISM(S): Homo sapiens 
2025-08-30 | E-MTAB-15495 | biostudies-arrayexpress
GenomicsEffect of depletion of HMOX1 on gene expression of AsPC-1 cells.
Effect of depletion of HMOX1 on gene expression of AsPC-1 cells.
PRJNA1007732 | ENA
GenomicsInhibition of HMOX1 alleviates diabetic cardiomyopathy by targeting ferroptosis
Inhibition of HMOX1 alleviates diabetic cardiomyopathy by targeting ferroptosis
PRJNA1006668 | ENA
GenomicsMelanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis.
Melanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis.
PRJNA1156790 | ENA
Genomics
Cut tag data of HMOX1
PRJNA1505043 | ENA
GenomicsMelanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis II
Melanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis II
PRJNA1156793 | ENA
GenomicsIFI16-mediated cellular senescence drives HMOX1-dependent evasion of ferroptosis and radioresistance in glioblastoma
IFI16-mediated cellular senescence drives HMOX1-dependent evasion of ferroptosis and radioresistance in glioblastoma
PRJNA1144925 | ENA
TranscriptomicsTranscriptional profile of knockdown of HMOX1 or/and pimozide-treated cancer cell lines
DRD2 antagonists are commonly used clinically for the treatment of psychiatric disorders. This study aimed to explore the antitumor effects of DRD2 antagonists on a variety of tumor entities. A DRD2 antagonist, pimozide, exhibited antitumor effects in pancreatic, colorectal, ovarian, and gastric can...
ORGANISM(S): Homo sapiens 
2025-08-30 | E-MTAB-15496 | biostudies-arrayexpress
UnknownHMOX1 promotes lung adenocarcinoma metastasis by affecting macrophages and mitochondrion complexes.
Not available
S-EPMC9417688 | biostudies-literature
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