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ProteomicsImpact of intermittent lead exposure on hominid brain evolution
Lead Exposure and Human Brain Evolution: A 2-Million-Year Perspective This study reveals that lead exposure was pervasive throughout human evolution, not just a modern phenomenon. Researchers analyzed 51 fossil teeth from multiple hominid species spanning 2+ million years across three continents, fi...
ORGANISM(S): Homo sapiens (Human) 
2025-10-27 | PXD067623 | Pride
Lead exposure  hominid brain evolution  nova1–foxp2 axis 
GenomicsLead exposure’s role in brain evolution
Impact of intermittent lead exposure on hominid brain evolution
PRJEB83863 | ENA
GenomicsCharacterization of a novel developmental gene regulatory network in hominid brain evolution
Hominid-specific transcription factors ZNF90 and OVOL2 drive a neotenic developmental program modelled in rhesus macaque cerebral organoids
PRJEB113819 | ENA
UnknownImpact of intermittent lead exposure on hominid brain evolution.
Not available
S-EPMC12527068 | biostudies-literature
TranscriptomicsComparative genomic hybridization of 5 hominid species, including humans
Given that gene duplication is a major driving force of evolutionary change and the key mechanism underlying the emergence of new genes and biological processes, this study sought to use a novel genome-wide approach to identify genes that have undergone lineage-specific duplications or contractions ...
ORGANISM(S): Homo sapiens 
2013-01-30 | E-SMDB-2855 | biostudies-arrayexpress
TranscriptomicsModeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees
Understanding evolutionary mechanisms underlying expansion and reorganization of the human brain represents an important aspect in analyzing the emergence of cognitive abilities typical of our species. Comparative analyses of neuronal phenotypes in closest living relatives (Pan troglodytes; the comm...
ORGANISM(S): Pan troglodytes 
2016-08-07 | E-GEOD-83638 | biostudies-arrayexpress
UnknownTempo and mode of gene expression evolution in the brain across primates.
Not available
S-EPMC10876213 | biostudies-literature
TranscriptomicsRNA-seq to investigate how human-specific Notch2 paralogs expand cortical neurogenesis through regulation of Delta/Notch interactions.
The human cerebral cortex underwent rapid enlargement and complexification during recent evolution. Hominid-specific (HS) genes arising from genomic duplications may be involved, but it remains unclear how much and which HS genes contribute to human brain development. Using tailored RNAseq profiling...
ORGANISM(S): Homo sapiens 
2018-04-06 | E-MTAB-6232 | biostudies-arrayexpress
UnknownEvolution of brain lateralization: A shared hominid pattern of endocranial asymmetry is much more variable in humans than in great apes.
Not available
S-EPMC7021492 | biostudies-literature
UnknownHeterochronies and allometries in the evolution of the hominid cranium: a morphometric approach using classical anthropometric variables.
Not available
S-EPMC9420405 | biostudies-literature
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