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ProteomicsDirect comparison of the hinge-cleaving proteases IgdE and BdpK for LC-MS based IgG1 clonal profiling
Human antibodies are heterogeneous molecules, primarily due to clonal sequence variations. Analytical techniques to assess antibody levels quantitatively, like ELISA assays, lack the power to determine abundances at the clonal level. Recently, we introduced an LC-MS-based approach that can distingui...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-17 | MSV000092676 | MassIVE
ProteomicsPrimary human natural killer cells retain proinflammatory IgG1 at the cell surface and express CD16a glycoforms with donor-dependent variability
Post-translational modification of NK cell CD16a and its IgG1 ligand
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-04 | MSV000083890 | MassIVE
ProteomicsHuman IgG1 (B-cell receptor) Fc peptide glycan analysis, LC-MS
Since few data are available on glycans expressed by human BCRs, we aimed to analyze the Fc glycans of membrane-bound IgG after BCR capture and tryptic digestion by LC-MS. For this purpose, human B-cell lines from Burkitt Lymphoma (Ramos) expressing IgG1-BCRs in the presence or absence of Fc glycans...
ORGANISM(S): Homo sapiens (Human) 
2023-12-11 | PXD047089 | Pride
Human B-cell receptor Igg1 fc peptide glycans Lc-ms 
GenomicsRNA-seq analysis of splenic IgG1 or IgM plasma cells
RNA-seq analysis of splenic IgG1 or IgM plasma cells
PRJNA1376052 | ENA
ProteomicsAnalysis of IgG1 producing CHO cells
The effects of changes in bioprocessing parameters (temp, pH, DO) on anti-IL8 IgG1 producing Chinese hamster ovary (CHO) cells were studied on the level of host cell proteome expression using TMT-SPS-MS3.
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2021-04-09 | PXD017779 | Pride
Sps-ms3 Tmt Cho 
TranscriptomicsExpression data from IgE+ and IgG1+ B lymphocytes in mice infected with Nippostrongylus brasiliensis
The mechanisms involved in the maintenance of memory IgE responses are poorly understood, and the role played by germinal center (GC) IgE cells in these memory responses is particularly unclear. IgE B-cell differentiation is characterized by a transient GC phase, a bias towards the plasma cell (PC) ...
ORGANISM(S): Mus musculus 
2013-10-31 | E-GEOD-49033 | biostudies-arrayexpress
GenomicsDifferential gene expression of human natural killer cells following immobilized IgG1 stimulation
Differential gene expression of human natural killer cells following immobilized IgG1 stimulation
PRJNA431411 | ENA
GenomicsTranscriptomics of BCR-stimulated IgG1 and IgG4 human B cell clones
Transcriptomics of BCR-stimulated IgG1 and IgG4 human B cell clones
PRJNA531947 | ENA
GenomicsRNA-seq analysis of germinal center-derived splenic IgG1 or IgM plasma cells
RNA-seq analysis of germinal center-derived splenic IgG1 or IgM plasma cells
PRJNA1374270 | ENA
TranscriptomicsExpression data from cell lines treated with enavatuzumab and human IgG1 control
Cancer lines were treated with enavatuzumab and a human IgG1 control (MSL109) in vitro. Samples were extracted at various time points and analyzed via genechip. We used microarrays to examine gene expression patterns following treatment with enavatuzamab. Expression changes over time were compared...
ORGANISM(S): Homo sapiens 
2013-10-31 | E-GEOD-51934 | biostudies-arrayexpress
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