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MetabolomicsRBC Balanced Immuno-inflammatory Signatures Identify Advanced Breast Cancer Patients on CDK4/6 Inhibitors at Increased Risk of Progression and Death

Recent studies show red blood cell (RBC) plays an essential role in regulating immunity. Nevertheless, the association of immuno-inflammatory parameters, especially RBC balanced signatures, with survival outcomes and adverse events still require investigation for advanced breast cancer (ABC) pati...

2025-04-15 | MTBLS10792 | MetaboLights
UnknownViral anti-inflammatory serpin reduces immuno-coagulopathic pathology in SARS-CoV-2 mouse models of infection.
Not available
S-EPMC10493584 | biostudies-literature
TranscriptomicsMerck Ad5/HIV induces broad innate immune activation that predicts CD8+ T-cell responses but is attenuated by preexisting Ad5 immunity.
This SuperSeries is composed of the following subset Series: GSE22768: Systems analysis of the Merck Ad5/HIV vaccine reveals robust induction of a core innate immune gene network: in vivo analysis GSE22769: Systems analysis of the Merck Ad5/HIV vaccine reveals robust induction of a core innate immun...
ORGANISM(S): Homo sapiens 
2012-11-20 | E-GEOD-22822 | biostudies-arrayexpress
UnknownMachine Learning-Based Immuno-Inflammatory Index Integrating Clinical Characteristics for Predicting Coronary Artery Plaque Rupture.
Not available
S-EPMC11973732 | biostudies-literature
UnknownProfiling Pro-Inflammatory Proteases as Biomolecular Signatures of Material-Induced Subcutaneous Host Response in Immuno-Competent Mice.
Not available
S-EPMC11792001 | biostudies-literature
UnknownMetabolic Dysfunctions of Intestinal Fatty Acids and Tryptophan Reveal Immuno-Inflammatory Response Activation in IgA Nephropathy.
Not available
S-EPMC8850467 | biostudies-literature
ProteomicsExtracellular Vesicles from the Probiotic Yeast Pichia kudriavzevii: Proteomic Characterization and Modulation of Immune and Defense Responses in an Induced Inflammation Model of Intestinal Epithelial Cells
Extracellular vesicles (EVs) derived from probiotics represent a new and exciting frontier in host-microbe therapeutics. These nanoscale carriers are not merely cellular byproducts but are sophisticated mediators of intercellular communication, capable of modulating immune responses, reducing inflam...
ORGANISM(S): Pichia kudriavzevii 
2026-04-06 | PXD069498 | Pride
Probiotics  pichia kudriavzevii  membrane vesicles  proteomics  immuno-inflammatory responses 
UnknownImmuno-pathogenesis of nCOVID-19 and a possible host-directed therapy including anti-inflammatory and anti-viral prostaglandin (PG J2) for effective treatment and reduction in the death toll.
Not available
S-EPMC7341031 | biostudies-literature
TranscriptomicsInflammatory and immune responses in lymph nodes of Iberian red deer infected with Mycobacterium bovis.
Bovine tuberculosis (bTB), caused by Mycobacterium bovis (Mycobacterium tuberculosis complex), is a zoonotic disease that affects cattle and wildlife worldwide. In some regions of Spain, Iberian red deer (Cervus elaphus hispanicus) can serve as reservoir of infection, thus increasing the risk of hum...
ORGANISM(S): Cervus elaphus hispanicus 
2007-10-17 | E-GEOD-6083 | biostudies-arrayexpress
TranscriptomicsT cell intrinsic STAT1 signaling prevents aberrant Th1 responses during acute toxoplasmosis
Infection-induced T cell responses must be properly tempered and terminated to prevent immuno-pathology. Using transgenic mice, we demonstrate that T cell intrinsic STAT1 signaling is required to curb inflammation during acute infection with Toxoplasma gondii. Specifically, we report that mice lacki...
ORGANISM(S): Mus musculus 
2023-07-10 | GSE236970 | GEO
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