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ProteomicsDirhodium (II) Complex Interferes with Iron-Transport System to Exert Antibacterial Action against Streptococcus pneumoniae
Drug resistance in bacteria is becoming a significant threat to global public health, and the development of novel and efficient antibacterial compounds is urgently needed. Recently, rhodium complexes have attracted attention as antimicrobial agents, yet their antibacterial mechanism remains unknown...
ORGANISM(S): Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) 
2022-02-28 | PXD011667 | Pride
Antibacterial mechanism Streptococcus pneumoniae Haem-transport system piuabcd Itraq Dirhodium (ii) complex 
ProteomicsListeria monocytogenes responded to dehydrocorydaline
Listeria monocytogenes is a foodborne pathogen, with relatively low incidence but high case-fatality. Phytochemicals have been recognized as a promising antimicrobial agent as an alternative to synthetic chemicals due to their safety and high efficacy with multi-target sites. This study identified a...
ORGANISM(S): Listeria Monocytogenes Egd Listeria Monocytogenes Egd-e 
2021-10-19 | PXD029222 |
TranscriptomicsBulk RNA-seq profiling the response of human first-trimester and term Hofbauer cells to Listeria monocytogenes infection in vitro
To understand the response of human Hofbauer cells to Listeria monocytogenes infection and how it differs between first trimester and term, we established an infection assay using primary human first-trimester and term Hofbauer cells isolated by fluorescence-activated cell sorting and cultured in vi...
ORGANISM(S): Homo sapiens 
2025-08-04 | E-MTAB-14086 | biostudies-arrayexpress
UnknownDevelopment of Rapid and Economic In Vitro Assay and Biorelevant Ex Vivo Biofilm Inhibition Wound Model to Test the Antibacterial Efficacy of Wound Dressings.
Not available
S-EPMC12361873 | biostudies-literature
TranscriptomicsTranscriptomics analysis reveals the molecular mechanisms of the antibacterial activity of gallium nitrate against Acinetobacter baumannii isolated from bloodstream infections
Purpose: The aim of this study was to explore the antibacterial effect and molecular mechanism of gallium nitrate [Ga(NO 3 ) 3 ] against Acinetobacter baumannii from bloodstream infection. Methods: A total of 40 A. baumannii with different antimicrobials susceptibility patterns were isolated from bl...
ORGANISM(S): Acinetobacter baumannii 
2022-01-27 | GSE194255 | GEO
MetabolomicsMetabolomic analysis of the mechanism of action of yerba mate extract on Salmonella Typhimurium
Background: Salmonella Typhimurium is a gram-negative enteropathogen that infects millions worldwide; the rapid emergence of antibiotic resistant strains has heightened the urgency of developing effective treatment for this pathogen. Previous studies have demonstrated that the aqueous extract of yer...
2017-02-16 | MTBLS359 | MetaboLights
UnknownSynthesis, Characterization, Antibacterial Properties, and In Vitro Studies of Selenium and Strontium Co-Substituted Hydroxyapatite.
Not available
S-EPMC8072711 | biostudies-literature
UnknownThe ThiL enzyme is a valid antibacterial target essential for both thiamine biosynthesis and salvage pathways in Pseudomonas aeruginosa.
Not available
S-EPMC7380198 | biostudies-literature
ProteomicsCrizotinib, Tyrosine Kinase Inhibitors, Create an Antibacterial Active against Gram-positive Bacteria by Targeting the CTP Synthetase PyrG
Abstract The infection of drug resistant bacteria seriously threats to public health, which makes it more urgent to find novel antibacterial compounds. Compared with traditional development approaches, drug repurposing provides a faster and more effective strategy to find new antimicrobial agents....
ORGANISM(S): Staphylococcus aureus 
2022-03-10 | PXD029546 | Pride
Infection Pyrg Keywords: crizotinib Gram-positive 
UnknownPressure-Spun Fibrous Surgical Sutures for Localized Antibacterial Delivery: Development, Characterization, and In Vitro Evaluation.
Not available
S-EPMC10561146 | biostudies-literature
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