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Lung cancer (LC) is still one of the most deadly cancers in the world, but there is a lack of non-invasive biomarkers to assist diagnosis and guide treatment. Herein, untargeted serum metabolomics of 57 LC patients and 59 HC people was performed based on gas chromatography-mass spectrography (GC-...

2025-04-29 | MTBLS1517 | MetaboLights

Neutrophils contribute to systemic lupus erythematosus (SLE) pathogenesis through ROS and NET production, and increased apoptotic debris which causes autoantibody production and immune complex formation. These processes drive inflammation and tissue damage. The aim of this study was to perform in...

2026-04-22 | MTBLS6259 | MetaboLights
Initial discovery-based analysis using data independent acquisition (DIA) can obtain deep proteome coverage with high data completeness; however, the development of targeted PRM assays based on subsequent bioinformatic predictions can be tedious and time-consuming because of the complexity of the ou...
ORGANISM(S): Homo sapiens (Human) 
2024-09-06 | PXD049405 | Pride
Transcriptomic Profiling of Lactotroph Pituitary Neuroendocrine Tumors via RNA Sequencing and Ingenuity Pathway Analysis
Cannabinoids are known to exert immunosuppressive activities. However, the mechanisms which contribute to these effects are unknown. Using lipopolysaccharide (LPS) to activate BV-2 microglial cells, we examined how Δ9-tetrahydrocannabinol (THC), the major psychoactive component of marijuana, and can...
ORGANISM(S): Mus musculus 
Understanding the molecular basis of sex differences in neural response to acute hypoxic insult has profound implications for the effective prevention and treatment of ischemic stroke. Global hypoxic-ischemic induced neural damage has been studied recently under the well-controlled, non-invasive, re...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2022-02-22 | PXD027528 | Pride

Introduction

Chronic inflammation is a hallmark of chronic wounds and inflammatory skin diseases. Due to a hyperactive and prolonged inflammation triggered by proinflammatory immune cells, transitioning to the repair and healing phase is halted. T cells may exacerbate the proinflammatory mil...
2025-07-09 | MTBLS9800 | MetaboLights
Transcriptomic Data Reveals MYC as an Upstream Transcriptional Regulator in Laying Hen Pre-ovulatory Follicles using Ingenuity Pathway Analysis
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