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“Dry eye” is a multi-factorial inflammatory disease affecting the ocular surface. Tear hyperosmolarity in dry eye contributes to inflammation and cell damage. Recent research efforts on dry eye have been directed towards biomarker discovery for diagnosis, response to treatment and disease mechanisms...
2015-08-31 | MTBLS214 | MetaboLights
The recent development within high-throughput technologies for expression profiling has allowed for parallel analysis of transcriptomes and proteomes in biological systems such as comparative analysis of transcript and protein levels of tissue regulated genes. Until now, such studies of have only in...
ORGANISM(S): Sus scrofa 
The effects of temperature on teleosts have been of strong interest for a long time, particularly because low temperature profoundly influences the physiological and behavioral processes of ectotherms, especially teleosts. However, the cold-tolerance characteristics of fish at a protein level remain...
ORGANISM(S): Takifugu fasciatus 
2019-05-09 | PXD010955 | Pride
The iTRAQ-LC–MS/MS strategy was used for quantitative analysis to reveal the global response of P. aeruginosa SJTD-1 to the stimuli of C18 alkane in this study. As a result, 476 proteins were identified with a significant different expression levels for the growth on n-octadecane, accounting for 8.4...
ORGANISM(S): Pseudomonas aeruginosa SJTD-1 
2022-02-22 | PXD000936 | Pride
Soybean (Glycine max) is susceptible to root rot when subjected to continuous cropping, and this disease can seriously diminish the crop yield. Herein, isobaric tag for relative and absolute quantitation (iTRAQ) labeling and liquid chromatography-tandem mass spectrometry (LC-MS/MS) were employed for...
ORGANISM(S): Glycine max 
2019-11-12 | PXD009911 | Pride
iTRAQ-based quantitative proteomic analysis of heat stress-induced mechanisms in pepper seedlings
ORGANISM(S): Capsicum annuum 
2021-05-06 | PXD019556 | Pride
After long-term aluminum treatment, thereafter, we investigated Citrus root protein profiles using isobaric tags for relative and absolute quantification (iTRAQ).
ORGANISM(S): Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis) Citrus maxima (Pomelo) (Citrus grandis) 
2017-10-26 | PXD002301 | Pride
Stable VPS35 knockdown HeLa cells were generated using lentiviral short hairpin RNA (shRNA) construct. Isobaric tags for relative and absolute quantitation (iTRAQ)-based mass spectrometry was used to measure the changes of nuclear protein abundance in VPS35-depleted HeLa cells.
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD027166 | Pride
Viscum coloratum (Kom.) Nakai is a variety of biological activities of medicinal plants, and the active component such as polysaccharides or alkaloids, also proved to have the effect of anti-tumor, anti-virus, anti-radiation, anti-oxidation and anti-infection. In this study, we examined the inhibiti...
ORGANISM(S): Homo sapiens (Human) 
2018-10-26 | PXD005323 | Pride
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