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TranscriptomicsKat2a regulates hippocampal memory formation [RNA-seq]
We sequenced mRNA from 24 samples extracted from mouse CA1 tissue to generate the first CA1-specific murine transcriptome and the first CA1-transcriptome in response to environmental novelty under normal and Kat2a-loss-of-function conditions. Samples were divded in 4 groups: A: Control naM-CM-/ve (n...
ORGANISM(S): Mus musculus 
2014-07-16 | E-GEOD-53380 | biostudies-arrayexpress
TranscriptomicsKat2a regulates hippocampal memory formation [small RNA-seq]
We sequenced small RNAs from 12 samples extracted from mouse CA1 tissue to generate the first CA1-specific murine miRNome under normal and Kat2a-loss-of-function conditions. Samples were divded in 4 groups: A: Control (n=6), C: Kat2a cKO naïve (n=6)
ORGANISM(S): Mus musculus 
2014-07-16 | E-GEOD-53427 | biostudies-arrayexpress
ProteomicsHuman KAT2A/B-acetylome MudPIT
Comprehensive identification of acetylated proteins targeted by the lysine acetyltransferases KAT2A (GCN5) and KAT2B (PCAF), in human cells. KAT2A/B-dependent acetylated proteins were identified by comparing acetylated proteins in whole cell extract of control cells and cells in which KAT2A and KAT2...
ORGANISM(S): Homo sapiens (Human) 
2016-12-12 | PXD004669 | Pride
Acetylation Non-histone targets Kat2a(gcn5) Centrosome duplication Kat2b (pcaf) Plk4 
ProteomicsIdentification of Aurora B phosphorylation mediated by KAT2A-treated PGK1 in vitro
The dataset was generated to characterize Aurora B phosphorylation following the KAT2A-PGK1 in vitro reaction.
ORGANISM(S): Homo sapiens (Human) 
2026-09-04 | PXD083647 | Pride
Human  hepatocellular carcinoma  hcc  lactate  protein lactylation  lysine lactylation  pgk1  k131  immunoprecipitation  lc-ms/ms  pgk1  aurora b  aurkb  kat2a  lactylation  phosphorylation 
ProteomicsDegron-independent recruitment of KAT2A redefines the breadth of CRBN-based molecular-glue targets
Lysine acetyltransferases (KATs) frequently cooperate with oncogenes such as c-Myc, estrogen receptor, and KMT2A-fusions to sustain malignant programs. Therapeutic targeting of KAT proteins has shown clinical efficacy, yet achieving homolog-selectivity for most KATs remains a major challenge. Here, ...
ORGANISM(S): Homo sapiens (Human) 
2026-08-29 | PXD072224 | Pride
Ubiquitin Kat2a Crbn Molecular glue Lysine acetyltransferases Protein degradation E3 ligase Aml 
ProteomicsDegron-independent recruitment of KAT2A redefines the breadth of CRBN-based molecular-glue targets
Lysine acetyltransferases (KATs) frequently cooperate with oncogenes such as c-Myc, estrogen receptor, and KMT2A-fusions to sustain malignant programs. Therapeutic targeting of KAT proteins has shown clinical efficacy, yet achieving homolog-selectivity for most KATs remains a major challenge. Here, ...
ORGANISM(S): Homo sapiens (Human) 
2026-08-29 | PXD072306 | Pride
Ubiquitin Kat2a Crbn Molecular glue Lysine acetyltransferases Protein degradation E3 ligase Aml 
GenomicsDisruption of the SAGA CORE triggers collateral degradation of KAT2A
Disruption of the SAGA CORE triggers collateral degradation of KAT2A
PRJNA1281528 | ENA
GenomicsTranscriptomic changes in HCT116 cells after KAT2A knockout
Transcriptomic changes in HCT116 cells after KAT2A knockout
PRJNA1035047 | ENA
GenomicsInvestigations of the roles of epigenetic regulator KAT2A in ccRCC
Investigations of the roles of epigenetic regulator KAT2A in ccRCC
PRJNA739744 | ENA
GenomicsTranscriptomic changes in primary intestinal epithelium cells with Kat2a/Kat2b DKO.
Transcriptomic changes in primary intestinal epithelium cells with Kat2a/Kat2b DKO.
PRJNA987626 | ENA
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