CCT6A is a key subunit of the TRiC complex and is responsible for the folding and maturation of approximately 10% of newly synthesized proteins in cells. Given that different TRiC subunits exhibit substrate specificity, we hypothesized that CCT6A might act as a specific binding subunit. To test this...
Lung squamous cell carcinoma cells were transfected by THOC3 overexpressed plasmids with FLag-tag. Then anti-Flag antibodies were utilized and proteins bound to THOC3 were analyzed by mass spectrometry.
