Sort   by:  
 Page size 
MetabolomicsAutomated Label-free Quantification of Metabolites from Liquid Chromatography–Mass Spectrometry Data (Simulated)

Liquid chromatography coupled to mass spectrometry (LC-MS) has become a standard technology in metabolomics. In particular, label-free quantification based on LC-MS is easily amenable to large-scale studies and thus well suited to clinical metabolomics. Large-scale studies, however, require autom...

2015-12-16 | MTBLS235 | MetaboLights
MetabolomicsAutomated Label-free Quantification of Metabolites from Liquid Chromatography–Mass Spectrometry Data (Plasma)

Liquid chromatography coupled to mass spectrometry (LC-MS) has become a standard technology in metabolomics. In particular, label-free quantification based on LC-MS is easily amenable to large-scale studies and thus well suited to clinical metabolomics. Large-scale studies, however, require autom...

2015-12-16 | MTBLS234 | MetaboLights
ProteomicsRobust collection and processing for label-free single voxel proteomics
With advanced mass spectrometry (MS)-based proteomics, genome-scale proteome coverage can be achieved from bulk tissues. However, such bulk measurement lacks spatial resolution and obscures important tissue heterogeneity, which make it impossible for proteome mapping of tissue microenvironment. Here...
ORGANISM(S): Homo Sapiens (human) 
2024-11-01 | PXD045043 | JPOST Repository
ProteomicsReproducibility of label-free single-shot phosphoproteomics applied to CRC cell lines
There is a need for robust phosphopeptide enrichment methods to allow signaling network analysis in cancer cell lines and tissues with minimal fractionation. With recent instrument developments thousands of unique phosphopeptides can be detected by single-shot LC-MS/MS. However, successful phosphopr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080715 | MassIVE
UnknownComparative Proteome Profiling of Saliva Between Estrus and Non-Estrus Stages by Employing Label-Free Quantitation (LFQ) and Tandem Mass Tag (TMT)-LC-MS/MS Analysis: An Approach for Estrus Biomarker Identification in Bubalus bubalis.
Not available
S-EPMC9217162 | biostudies-literature
ProteomicsComparison of LFQ and TMT-based quantitative proteomics towards toxicology research
Here, we aimed to compare two of the most commonly used global proteomics strategies, label-free quantification (LFQ) and tandem mass tag-based quantification (TMT) to identify the most suitable tool for toxicology research questions on the systemic level. Using a biological case study of HepG2 expo...
ORGANISM(S): Homo sapiens (Human) 
2020-12-23 | PXD020248 | Pride
Toxicoproteomics Benzo[a]pyrene Tandem mass tag (tmt) Label free-quantification (lfq) Hepg2 
ProteomicsIdentification of Potential Protein Biomarkers for Early Detection of Pregnancy in Cow Urine uses 2D DIGE and Label Free quantitation
Background: An early, reliable and noninvasive method of pregnancy diagnosis is a prerequisite for efficient reproductive management in dairy industry. The early detection of pregnancy also helps to reduce the calving interval and rebreeding time which is beneficial for farmers and dairy industries....
ORGANISM(S): Bos taurus (Bovine) 
2018-10-26 | PXD004122 | Pride
Dige Gene ontology Lfq Decyder Cow Urine Lc-ms/ms 
ProteomicsStaphylococcus aureus Secretome Profiling using Label Free Quantitation
The application of label free quantitation (LFQ) to the profiling of secreted proteomes is a powerful tool in the deciphering of these mechanisms and the determination of the severity of infection with different strains. Our study consists of three distinct, but interconnected experiments resulting ...
ORGANISM(S): Staphylococcus Aureus (ncbitaxon:1280) 
2016-10-21 | MSV000080260 | MassIVE
ProteomicsQuantitation of ATIs in Wheat by LC-MS/MS – LFQ Orbitrap
A selection of ATIs was silenced in the common wheat cultivar Bobwhite and durum wheat cultivar Svevo by RNAi and gene editing, respectively, in order to reduce the amounts of ATIs. The controls and silenced lines were analyzed after digestion to peptides by LC-MS/MS with different approaches to eva...
ORGANISM(S): Triticum aestivum (Wheat) Triticum durum 
2022-10-13 | PXD034458 | Pride
Amylase/trypsin inhibitor  wheat  crsipr-cas9  rnai 
ProteomicsLFQ Analysis of Differential Protein Regulation in Response to Tween-20 Exposure in TwnR mutant Myxococcus xanthus strains
A time series study was performed on detergent exposure in TwnR mutant (2242mut) to observe differential protein abundances between groups using label free quantitation (LFQ).
ORGANISM(S): Myxococcus xanthus 
2024-07-26 | PXD053714 | Pride
Detergent resistance Myxococcus xanthus Mutant Label free quantitation Time-series 
Sort   by:  
 Page size