Sort   by:  
 Page size 
GenomicsA Prader-Willi locus lncRNA cloud modulates diurnal genes and energy expenditure.
Prader-Willi syndrome (PWS), a genetic cause of childhood obesity, is characterized by intellectual disabilities and sleep abnormalities. PWS-causing deletions include a neuronal long, non-coding RNA (lncRNA) processed into small nucleolar RNAs and a spliced lncRNA,116HG. We show that 116HG forms a ...
ORGANISM(S): Mus musculus 
2013-06-20 | E-GEOD-43575 | biostudies-arrayexpress
TranscriptomicsThe evolution of lncRNA repertoires and expression patterns in tetrapods
Only a minuscule fraction of long non-coding RNAs (lncRNAs) are well characterized. The evolutionary history of lncRNAs can provide insights into their functionality, but comparative analyses have been precluded by our ignorance of lncRNAs in non-model organisms. Here, we use RNA sequencing to ident...
ORGANISM(S): Ornithorhynchus anatinus 
2014-01-19 | E-GEOD-43520 | biostudies-arrayexpress
TranscriptomicsLong non-coding RNAs act as novel mediators of Innate Immunity
Recent advances in genome technologies have uncovered thousands of long non-coding RNAs (lncRNAs) whose function in the immune system has been largely unexplored. Members of the Toll-like receptor (TLR) family activate an inducible program of inflammatory genes important in host defenses. Here we p...
ORGANISM(S): Mus musculus 
2013-08-26 | E-GEOD-40978 | biostudies-arrayexpress
ProteomicsComprehensive Identification of Soybean Long Non-coding RNAs Reveals a Subset of Small Peptide-Coding Transcripts
Long non-coding RNAs (lncRNAs) are defined as non-protein-coding transcripts that are at least 200 nucleotides long. They are known to play pivotal roles in regulating gene expression, especially during stress responses in plants. We used a large collection of in-house transcriptome data from variou...
ORGANISM(S): Glycine max 
2020-01-09 | PXD014553 | Pride
Long non-coding rna Proteomics Soybean Small peptide Transcriptomics 
TranscriptomicsLong non-coding RNA expression profiling in the NCI60 cancer cell line panel using high-throughput RT-qPCR
Long non-coding RNAs (lncRNAs) form a new class of RNA molecules implicated in various aspects of protein coding gene expression regulation. To study lncRNAs in cancer, we generated expression profiles for 1708 human lncRNAs in the NCI60 cancer cell line panel using a high-throughput nanowell RT-qPC...
ORGANISM(S): Homo sapiens 
2016-06-29 | E-GEOD-80332 | biostudies-arrayexpress
ProteomicsCRISPR-assisted RNA-protein interaction detection (CARPID) combined with quantitative mass spectrometry was used to identify proteins interacting with the long non-coding RNA (lncRNA) Taurine Up-regulated 1 (TUG1) in HEK293T cells under physiological conditions and after Camptothecin (CPT) treatment.
This project utilized CRISPR-assisted RNA-protein interaction detection (CARPID) combined with mass spectrometry to identify proteins interacting with the long non-coding RNA (lncRNA) TUG1 in HEK293T cells. TUG1 preferentially interacts with known R-loop-associated proteins, particularly under Campt...
ORGANISM(S): Homo Sapiens (human) 
2025-07-17 | PXD049137 | JPOST Repository
TranscriptomicsLncRNA and mRNA expression data involved in benzene hematotoxicity
Benzene is a ubiquitous environmental pollutant and an established human hematotoxicant and leukemogen. New insights into the pathogenesis of benzene hematotoxicity are urgently needed. Long non-coding RNA（lncRNA）can regulate gene expression and widely participate in the various physiological and pa...
ORGANISM(S): Homo sapiens 
2015-07-27 | E-GEOD-50737 | biostudies-arrayexpress
GenomicsCustom long non-coding RNA capture enhances detection sensitivity in different human sample types.
Long non-coding RNAs (lncRNAs) are a heterogeneous group of transcripts that lack protein coding potential and display regulatory functions in various cellular processes. As a result of their cell- and cancer-specific expression patterns, lncRNAs have emerged as potential diagnostic and therapeutic ...
EGAS00001005418 | EGA
TranscriptomicsControl of Somatic Tissue Differentiation by the Long Non-Coding RNA TINCR (HTS)
Several of the thousands of human long non-coding RNAs (lncRNAs) have been functionally characterized; however, potential roles for lncRNAs in somatic tissue differentiation remain poorly understood. Here we show that a 3.7kb lncRNA, terminal differentiation-induced ncRNA (TINCR), controls human epi...
ORGANISM(S): Homo sapiens 
2012-10-10 | E-GEOD-40121 | biostudies-arrayexpress
TranscriptomicsThe DNMT1 associated lncRNA Dali is an epigenetic regulator of neural differentiation [3]
Many intergenic long noncoding RNA (lncRNA) loci regulate the expression of adjacent protein coding genes. Less clear is whether intergenic lncRNAs commonly regulate transcription by modulating chromatin at genomically distant loci. Here, we report both genomically local and distal RNA-dependent rol...
ORGANISM(S): Mus musculus 
2014-12-03 | E-GEOD-62033 | biostudies-arrayexpress
Sort   by:  
 Page size