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ProteomicsXylem sap shotgun proteomics from Fe- and Mn-deficient and Mn-toxic tomato plants
The aim of this work was to study the effects of Fe and Mn deficiencies and Mn toxicity on the protein profile of the xylem sap of tomato (Solanum lycopersicum), with the aim of elucidating plant response mechanisms to these nutritional stresses. Tomato was chosen as a model plant because the tomato...
ORGANISM(S): Viridiplantae 
2017-11-30 | PXD007517 | Pride
Iron deficiency  mn deficiency  mn toxicity  shotgun proteomics  tomato  xylem sap 
ProteomicsSystems-wide analysis of manganese deficiency-induced changes in gene activity of Arabidopsis roots
In this study, we undertook a comprehensive quantitative proteomic profiling of Arabidopsis roots from plants grown on Mn-deplete media, aiming at dissecting and cataloging the responses of Arabidopsis roots to Mn deficiency. We used LC-Q Exactive Orbitrap mass spectrometer to compile a near complet...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-10-26 | PXD003309 | Pride
Proteomics Manganese deficiency Systems biology Transcriptomics Post-transcriptional regulation 
ProteomicsRoot shotgun proteomics from Fe- and Mn-deficient and Mn-toxic tomato plants
The aim of this work was to study the effects of Fe and Mn deficiencies and Mn toxicity on the protein profile of the root of tomato (Solanum lycopersicum), with the aim of elucidating plant response mechanisms to these nutritional stresses. Tomato was chosen as a model plant because the tomato geno...
ORGANISM(S): Solanum lycopersicum 
2018-08-06 | PXD008326 | Pride
Iron deficiency  mn deficiency  mn toxicity  shotgun proteomics  tomato  root 
TranscriptomicsTranscription profiling of human astrocytes to create a toxicogenomic profile of Mn
Exposure of adult humans to manganese (Mn) has long been known to cause neurotoxicity. Recent evidence also suggests that exposure of children to Mn is associated with developmental neurotoxicity. Astrocytes are critical for the proper functioning of the nervous system, and they play active roles ...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-5079 | biostudies-arrayexpress
ProteomicsProteomic Analysis on the Mechanism of Iron-Compensation Substitute for Manganese Deficiency of Streptococcus pneumoniae
Iron (Fe) and Manganese (Mn) are essential for bacterial survival and virulence as they are involved in catalysis, infection and biofilm formation. The basal metabolism of pathogenic bacteria would be disturbed by the deficiency of metal ions in the host environment. In this study, we found that Str...
ORGANISM(S): Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) 
2023-09-30 | PXD008652 | Pride
Manganese deficiency Iron-compensation Proteomic Streptococcus pneumoniae 
MetabolomicsElevated brain manganese induces motor disease by upregulating the kynurenine pathway of tryptophan metabolism
Elevated brain levels of the essential metals manganese (Mn), copper, or iron induce motor disease. However, mechanisms of metal-induced motor disease are unclear and treatments are lacking. Elucidating the mechanisms of Mn-induced motor disease is particularly important because occupational and env...
2025-03-31 | MTBLS975 | MetaboLights
TranscriptomicsMouse ES-derived motor neurons (ES-MN) exposed to SOD1 mutant mouse astrocyte conditioned media
This datased was used to obtain a genome-wide expression signature for the early response of mouse motor neurons to mutant SOD1 astrocytes conditioned media. Neurons, far from living in isolation, are surrounded by a host of other neuronal and non-neuronal cells, such as astrocytes. The latter enter...
ORGANISM(S): Mus musculus 
2014-12-17 | E-GEOD-49023 | biostudies-arrayexpress
TranscriptomicsRosette iron deficiency transcript profiling in Arabidopsis thaliana ecotypes Kas-1 and Tsu-1
Iron (Fe) is an essential plant micronutrient, and its deficiency limits plant growth and development on alkaline soils. Under Fe deficiency, plant responses include upregulation of genes involved in Fe uptake from the soil. However, little is known about shoot responses to Fe deficiency. Using m...
ORGANISM(S): Arabidopsis thaliana 
2012-09-30 | E-GEOD-39268 | biostudies-arrayexpress
TranscriptomicsIron (Fe) deficiency in Citrus
Transcription profiling of citrus rootstock Poncirus trifoliata (L.) Raf. Keywords: Abiotic stress (Iron chlorosis) Total RNA from four replicates for each sample category (Poncirus trifoliata (L.) Raf watered for 60 days with 18 uM Fe-EDDHA or without Fe-EDDHA) were generated and compared.
ORGANISM(S): Poncirus trifoliata 
2010-05-19 | E-GEOD-17255 | biostudies-arrayexpress
TranscriptomicsEarly Iron Deficiency Induced Changes in Arabidopsis Roots
Due to limited bio-availability of Fe, plants evolved adaptive alterations in development regulated at the transcriptional level. We investigated the early transcriptional response to Fe deficiency. A hydroponic system was used that allows bulk transferring of plantsand rapid Fe removal with little ...
ORGANISM(S): Arabidopsis thaliana 
2009-03-13 | E-GEOD-15189 | biostudies-arrayexpress
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