monocyte/macrophages

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Unknown (4076)
Transcriptomics (3071)
Genomics (1742)
Proteomics (263)
Metabolomics (92)
Other (37)
Methylation profiling (7)
Multiomics (3)
Models (2)

Organisms

Mus musculus (1760)
Homo sapiens (1447)
Rattus norvegicus (59)
Sus scrofa (41)
Mycobacterium tuberculosis (36)
Bos taurus (31)
Francisella tularensis (12)
Gallus gallus (12)
Danio rerio (11)
Canis lupus familiaris (10)
Mycobacterium tuberculosis H37Rv (9)
Drosophila melanogaster (8)
Salmonella enterica subsp. enterica serovar Typhimurium (7)
Escherichia coli (7)
Yersinia pestis (6)
Candida albicans (6)
Mycobacterium avium subsp. paratuberculosis (5)
Salmo salar (5)
Brucella canis (4)
Salmonella enterica (4)
Macaca mulatta (4)
Felis catus (3)
Aspergillus fumigatus (3)
Listeria monocytogenes (3)
Ovis aries (3)
Mycobacterium avium subsp. paratuberculosis K-10 (3)
Leishmania major (3)
Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (2)
Brucella melitensis bv. 1 str. 16M (2)
Leishmania donovani (2)

Organisms

Homo sapiens (617)
Mus musculus (544)
Bos taurus (13)
Sus scrofa (10)
Rattus norvegicus (6)
Canis lupus familiaris (3)
Mycobacterium tuberculosis (3)
Macaca fascicularis (2)
Equus caballus (2)
Danio rerio (2)
Gallus gallus (2)
Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (1)
Mycobacterium avium subsp. paratuberculosis K-10 (1)
Mycobacterium avium subsp. hominissuis (1)
Mesocricetus auratus (1)
Nothobranchius furzeri (1)
Mus musculus musculus (1)
Mus (1)
Ovis aries (1)
Capra hircus (1)

Repository

biostudies-arrayexpress (2249)
ENA (1349)
geo (1067)
EGA (190)
pride (98)
MetaboLights (92)
MassIVE (87)
iProX (37)
jPOST (32)
ExpressionAtlas (7)
GPMDB (5)
PanoramaPublic (5)
PAXDB (2)
BioModels (1)
Cell Collective (1)

Tissue

Macrophage (53)
Cell culture (23)
Blood (20)
Monocyte (18)
Bone marrow (6)
Blood cell (5)
Liver (5)
Primary cell (5)
Dendritic cell (3)
Epithelial cell (2)
Hepatocyte (2)
Osteoclast (2)
Muscularis externa layer of small intestine (1)
Lamina propria of small intestine (1)
Ascites (1)
Blood plasma (1)
Blood serum (1)
Brain (1)
CD14-positive monocyte (1)
Cell lysate (1)
Chest muscle (1)
Embryonic stem cell (1)
Endometrial gland (1)
Endothelial cell (1)
Endothelial cell of hepatic sinusoid (1)
Endothelial cell of umbilical vein (1)
Femur (1)
HiPSC cell (1)
Lung (1)
Milk (1)

Disease

Normal (9)
Disease free (7)
Not Available (5)
Human immunodeficiency virus infectious disease (4)
Influenza (3)
Malignant neoplasm of ovary (3)
Inflammatory bowel disease (2)
COVID-19 (2)
Tumor bearing (1)
Pulmonary arterial hypertension (1)
HIV encephalitis (1)
Yersinia enterocolitica WAP infected (virulent) (1)
HIV-associated dementia (1)
Moderate (1)
Schizophrenia (1)
Mild asthma (1)
No tendon xanthomas (1)
Rheumatoid arthritis (1)
HIV-Tuberculosis with Immune Reconstitution Inflammatory Syndrome (1)
Leukemia (1)
SS2-infected (1)
Viral myocarditis (1)
Infected with Leishmania amazonensis (1)
Obesity (1)
C. burnetii infected (1)
Acute promyelocytic leukemia (1)
VSV infection (1)
Adenocarcinoma (1)
Multiple myeloma (1)
Control (1)

Technology Type

Mass Spectrometry (98)
Mass spectrometry (58)
Shotgun proteomics (43)
Mass spectrometry assay (33)
Bottom-up proteomics (24)
Data-dependent acquisition (19)
Gel-based experiment (10)
Data-independent acquisition (9)
SWATH MS (8)
Affinity purification coupled with mass spectrometry proteomics (7)
ILLUMINA, Illumina HiSeq 2000 (3)
Illumina HiSeq 2000 (3)
DiaPASEF (3)
Illumina HiSeq 2000, ILLUMINA (2)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
ILLUMINA, NextSeq 500 (1)
Illumina HiSeq 2500, ILLUMINA (1)
Illumina HiSeq 2000, NextSeq 500, ILLUMINA (1)
Illumina Human Custom 1, Illumina Human-Ref-8 v3 beadchip, 2M and Human 610 Quad Custom arrays (1)
Illumina MiSeq (1)
NMR spectroscopy assay (1)
Affinity proteomics (1)
All-ion fragmentation (1)
Glycoproteomics (1)
MSE (1)
SRM/MRM (1)
Top-down proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (74)
NextSeq 500 (46)
Illumina HiSeq 2000 (42)
Illumina HiSeq 4000 (39)
Illumina HiSeq 2500 (28)
Illumina HiSeq 1500 (20)
NextSeq 550 (18)
NextSeq 2000 (11)
Illumina NovaSeq X (10)
BD Rhapsody (3)
10x Genomics Chromium (3)
G2565AA DNA microarray scanner [Agilent] (3)
Illumina Genome Analyzer II (3)
NA (3)
DNBSEQ-G400 (3)
HiSeq X Ten (3)
Not applicable (2)
Generation III Array Scanner [Amersham] (2)
Bioanalyser (2)
418 [Affymetrix] (2)
GenePix 4000B [Axon Instruments] (2)
N/A (2)
Illumina HiSeq 1000 (2)
Illumina MiSeq (2)
Illumina HiSeq 3000 (2)
NanoDrop 2000 spectrophotometer (1)
DNBelab C Series High-throughput Single-cell RNA Library Preparation Set V3.0 (MGI Tech) (1)
DNBelab C-TaiM droplet generator (MGI Tech) (1)
Avatarget 12-well dual-chamber organ-on-chip system; AvatarFlow Organ Chip Flow Initiation Controller System (Avatarget Co., Ltd., Suzhou, China) (1)
Digital Alliance of Canada (1)

Publication Date

2025 (277)
2014 (273)
2015 (270)
2026 (262)
2013 (256)
2010 (239)
2012 (224)
2024 (214)
2016 (197)
2011 (197)
2023 (176)
2022 (162)
2008 (162)
2021 (143)
2020 (130)
2009 (121)
2019 (95)
2007 (84)
2017 (73)
2018 (68)
2006 (24)
2005 (10)
2004 (8)
2003 (6)

UNIPROT ID/AC

5DNU_SALTY (1)
6PGD_SALTY (1)
6PGL_SALTY (1)
99287.STM2621 (1)
99287.STM2628 (1)
99287.STM2632 (1)
99287.STM3813 (1)
99287.STM3814 (1)
99287.STM3815 (1)
99287.STM4146 (1)
AAC6_SALTY (1)
AAS_SALTY (1)
AAT_SALTY (1)
ABDH_SALTY (1)
ACCA_BORPE (1)
ACCA_SALTY (1)
ACCD_SALTY (1)
ACEA_SALTY (1)
ACEK_SALTY (1)
ACKA_SALTY (1)
ACNA_SALTY (1)
ACNB_SALTY (1)
ACP_BORPE (1)
ACP_SALTY (1)
ACSA_SALTY (1)
ACYP_SALTY (1)
ADD_SALTY (1)
AGAL_SALTY (1)
AGP_SALTY (1)
AHPC_SALTY (1)

CHEBI ID

CHEBI:17596 (20)
CHEBI:16708 (19)
CHEBI:16919 (18)
CHEBI:16335 (17)
CHEBI:15891 (17)
CHEBI:16027 (17)
CHEBI:17368 (17)
CHEBI:32816 (16)
CHEBI:30915 (16)
CHEBI:16737 (16)
CHEBI:30769 (16)
CHEBI:17562 (15)
CHEBI:16750 (15)
CHEBI:15741 (15)
CHEBI:18012 (15)
CHEBI:17858 (14)
CHEBI:16704 (14)
CHEBI:16856 (13)
CHEBI:16015 (13)
CHEBI:16264 (12)
CHEBI:17822 (12)
CHEBI:17361 (12)
CHEBI:15428 (12)
CHEBI:16235 (12)
CHEBI:17568 (12)
CHEBI:17509 (12)
CHEBI:16467 (12)
CHEBI:15603 (12)
CHEBI:15978 (11)
CHEBI:48928 (11)

Metabolite Name

Hypoxanthine (23)
Creatinine (21)
Adenine (19)
Creatine (19)
Uracil (17)
Betaine (16)
Ornithine (16)
Choline (16)
Adenosine (16)
Cytosine (16)
Taurine (15)
Inosine (15)
L-Tryptophan (14)
Uric acid (14)
Cytidine (14)
Guanosine (14)
Indole (13)
Xanthine (13)
L-Tyrosine (13)
5-Aminopentanoic acid (12)
Thymine (12)
Pyridoxine (12)
Guanine (12)
L-Phenylalanine (12)
Histidine (11)
Glycine (11)
Thiamine (11)
Pantothenic acid (11)
Citric acid (11)
Arginine (11)

First Public Date

2025 (192)
2024 (182)
2026 (177)
2023 (150)
2014 (125)
2022 (118)
2021 (91)
2020 (88)
2019 (65)
2017 (55)
2018 (37)
2015 (33)
2016 (27)
2013 (9)

Modelling Approach

Ordinary differential equation model (1)

Lab affiliation

Faculty of Chemistry and Center for Synthetic Microbiology (SYNMIKRO) Head of the Core-Facility for Mass Spectrometry Marburg University Hans-Meerwein-Str. 4 35032 Marburg GERMANY (2)
Infectious Diseases and Immunity in Global Health Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada (2)
School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland (2)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (2)
Alexander Schmidt, Biozentrum, University of Basel Spitalstrasse 41, CH-4056 Basel, Switzerland Tel. +41 61 207 0927, https://www.biozentrum.unibas.ch (1)
Alexander Schmidt, Biozentrum, University of Basel, Spitalstrasse 41, CH-4056 Basel, Switzerland, Tel. +41 61 207 0927, https://www.biozentrum.unibas.ch (1)
Assistant Professor Department of Cellular and Molecular Medicine Florida International University | Herbert Wertheim College of Medicine (1)
Associate Professor Translational Health Science and Technology Institute NCR Biotech Science Cluster 3rd Milestone,Gurugram-Faridabad Expressway Faridabad-121001 (1)
Associate professor at Macquarie University, Sydney, Australia Visiting professor at Institute for Glyco-core Research (iGCORE), Nagoya Univeristy, Aichi, Japan (1)
CABIMER (1)
CABIMER-University of Sevilla (1)
CIR, Queen’s Medical Research Institute, University of Edinburgh (1)
Cell Signalling and Immunology Division, School of Life Sciences, University of Dundee (1)
Cellular and Molecular Immunology Research Unit (CMIRU), Faculty of Allied Health Science, Naresuan University, Phitsanulok, Thailand (1)
Center for Tumor Biology and Immunology (ZTI), Philipps University, Hans-Meerwein-Strasse 3, 35043 Marburg, Germany (1)
Core Facility - High-Throughput Mass Spectrometry, Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health (BIH), Berlin, Germany (1)
Department of Anatomy and Cell Biology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA (1)
Department of Anesthesiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China (1)
Department of Biochemistry and Chemistry, Centre for Cardiovascular Biology and Disease Research, La Trobe Institute for Molecular Science, School of Agriculture, Biomedicine and Environment, La Trobe University, Bundoora, Victoria 3086, Australia (1)
Department of Biochemistry and Chemistry, Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC 3086, Australia (1)
Department of Biological Engineering, MIT, Cambridge, USA Ragon Institute of Mass General, Harvard, and MIT, Cambridge, USA (1)
Department of Biology, University of Crete, Heraklion, Crete, Greece; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, GR70013, Heraklion, Crete, Greece (1)
Department of Biomolecular Sciences University of Urbino "Carlo Bo" Campus Scientifico Enrico Mattei, Via Cà le Suore, 2 61029 Urbino (PU) ITALY (1)
Department of Dermatology and Venereology, University of Cologne, Faculty of Medicine, and University Hospital of Cologne; Cologne, Germany Center of Molecular Medicine Cologne (CMMC), University of Cologne; Cologne, Germany (1)
Department of Medicine, Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA (1)
Department of Molecular Genetics, Weizmann Institute of Science, Israel (1)
Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research - UFZ,Leipzig, Germany (1)
Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute Jena (Leibniz-HKI) (1)
Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam, the Netherlands; 3Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands (1)
Department of Obstetrics and Gynecology, School of Medicine, Stanford University, CA, USA. Igenomix Foundation, Instituto de Investigación Sanitaria Hospital Clínico (INCLIVA), Valencia, Spain (1)

IsPrivate

False (1)

Classification

bacteria (6)

Study type

Transcription profiling by array (1543)
RNA-seq of coding RNA (305)
ChIP-seq (105)
RNA-seq of coding RNA from single cells (61)
Unknown experiment type (48)
RNA-seq of total RNA (21)
RNA-seq of non coding RNA (21)
Transcription profiling by RT-PCR (19)
Other (16)
Methylation profiling by array (10)
Human - High-throughput sequencing (7)
Cell line - High-throughput sequencing (6)
Comparative genomic hybridization by array (6)
Methylation profiling by high throughput sequencing (6)
Transcription profiling by SAGE (5)
Animal - High-throughput sequencing (5)
ATAC-seq (5)
Proteomic profiling by array (5)
Human - One-color microarray (4)
MicroRNA profiling by array (4)
DNA-seq (4)
ChIP-chip by tiling array (3)
One-color microarray (3)
High-throughput sequencing (3)
Transcription profiling by tiling array (3)
MicroRNA profiling by high throughput sequencing (3)
Cell line - Single-cell sequencing (2)
Animal - One-color microarray (2)
Genotyping by array (2)
Spatial transcriptomics by high-throughput sequencing (2)

Release Date

2022 (449)
2023 (441)
2021 (440)
2015 (402)
2025 (385)
2014 (385)
2016 (381)
2024 (373)
2020 (370)
2019 (315)
2013 (315)
2012 (306)
2010 (295)
2018 (285)
2011 (272)
2017 (251)
2008 (177)
2009 (161)
2026 (117)
2007 (93)
2006 (38)
2005 (22)
2004 (12)
2003 (11)
2002 (8)
2001 (6)
2000 (5)
1998 (5)
1999 (3)
1997 (2)

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microRNA profiling of human monocytes and monocyte-derived macrophages

microRNA profiling data includes biological replicates of primary monocytes and macrophages from three human donors Dye swap hybridization arrays were performed for total RNA isolated from fresh monocytes and 7-day monocyte-derived macrophages from each of three human donors

ORGANISM(S): Homo sapiens

2013-05-10 | E-GEOD-39905 | biostudies-arrayexpress

Inhibition of Peripheral Serotonin Activates Hepatic AMPK and Reduces Monocyte-Derived Liver Macrophages, Ameliorating Obesity-Associated Fibrosis

Monocyte-derived liver macrophages are critical in the pathogenesis of metabolic dysfunction-associated steatohepatitis (MASH) and liver fibrosis, but their recruitment mechanisms remain unclear. Serotonin (5-hydroxytryptamine, 5HT) is a conserved monoamine synthesized by tryptophan hydroxylase (Tph...

ORGANISM(S): Mus musculus

2025-10-30 | E-MTAB-15760 | biostudies-arrayexpress

Transcription profiling of human peripheral blood monocyte (MONO), human peripheral blood monocyte derived macrophages treated with M-CSF (MACRO)and primary alveolar macrophages (BAL)

In order to study the gene expression profiles of monocyte and macrophages, we collected three type of cells and performed pair-wised comparison. It includes human peripheral blood monocyte (MONO), human peripheral blood monocyte derived macrophages treated with M-CSF (MACRO)and primary alveolar mac...

ORGANISM(S): Homo sapiens

2006-12-01 | E-MEXP-524 | biostudies-arrayexpress

The cellular and proteomic response of primary and immortalized murine Kupffer cells following immune stimulation diverges from that of monocyte-derived macrophages

Kupffer cells are the first line of defense in the liver against pathogens, yet several microbes successfully target the liver, bypass immune surveillance, and effectively develop in this tissue. Our current, albeit poor, understanding of Kupffer cell-pathogen interactions has been largely achieved ...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-22 | MSV000079995 | MassIVE

Transcriptome profile of human dermal macrophages and monocyte-derived macrophages

DC, monocyte and macrophage networks are evolutionarily conserved but the distinct subsets have been difficult to distinguish due to shared overlapping phenotypic markers between the cells. Using transcriptome microarray profiling of human and mouse mononuclear phagocyte subsets, we have distinguish...

ORGANISM(S): Homo sapiens

2014-10-15 | E-GEOD-60317 | biostudies-arrayexpress

Infiltrating monocyte-derived macrophages and resident kupffer cells display different ontogeny and functions in acute liver injury

Molecular profiling of infiltrating monocyte-derived macrophages versus resident kupffer cells following acute liver injury The liver has a remarkable capacity to regenerate after injury; yet, the role of macrophages (MF) in this process remains controversial mainly due to difficulties in distinguis...

ORGANISM(S): Mus musculus

2014-08-01 | E-GEOD-55606 | biostudies-arrayexpress

Transcription profiling of human monocyte derived macrophages reveals induction of dendritic cell-like phenotype in macrophages during foam cell formation

Foam cell formation from monocyte-derived macrophages is a hallmark of atheroscle-rotic lesions. Aspects of this process can be recapitulated in vitro by exposing MCSF-induced or platelet factor4 (CXCL4)-induced macrophages to oxidized (ox) or minimally modified (mm) low density lipoprotein (LDL). W...

ORGANISM(S): Homo sapiens

2008-06-15 | E-GEOD-7138 | biostudies-arrayexpress

Transcriptional responses of human monocyte-derived macrophages (HMDM) to lipopolysaccharide (LPS) - Illumina arrays

These microarrays were performed for use in a genome-wide scan for LPS-regulated genes in human monocyte-derived macrophages, in order to construct a list of LPS-regulated genes for detailed interrogation on custom microarrays (see GSE19482 for custom array analysis). Human monocyte-derived macropha...

ORGANISM(S): Homo sapiens

2012-03-28 | E-GEOD-19765 | biostudies-arrayexpress

Genome-wide analysis of monocyte derived macrophages from Crohn's Disease patients and controls

Crohn's disease (CD) is a complex and highly heterogeneous chronic inflammatory disorder, primarily affecting the gastrointestinal tract. Genetic and functional studies have highlighted a key role for innate immunity in its pathogenesis. Profound systemic defects in innate immunity and acute inflamm...

ORGANISM(S): Homo sapiens

2014-08-06 | E-GEOD-60083 | biostudies-arrayexpress

Transcription profiling of activated mixed glial (microglia) and monocyte-derived macrophages

Since macrophage activation can now be studied at a global level using modern microarray and proteomic analyses, discovery of novel macrophage activation genes is inevitable and important for understanding HIV-associated dementia (HAD). We isolated two different types of primary human macrophages, m...

ORGANISM(S): Homo sapiens

2007-08-29 | E-GEOD-1910 | biostudies-arrayexpress

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