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ProteomicsCirculating levels of the proinflammatory monomeric isoform of C-reactive protein (mCRP) correlate with intra-tumoral mCRP abundance in stage II-III colon cancer patients
Elevated levels of circulating C-reactive protein (CRP) are associated with worse outcome for patients with colorectal cancer (CRC). Monomeric CRP (mCRP) has been demonstrated in tissues of various diseases, including colon cancer (CC). mCRP possesses proinflammatory properties and potentially contr...
ORGANISM(S): Homo sapiens (Human) 
2025-06-16 | PXD046746 | Pride
Colon cancer Inflammation Monomeric c-reactive protein C-reative protein Biomarker 
ProteomicsThe Influences of ApoE Isoforms on Endothelial Adherens Junctions and Actin Cytoskeleton Responding to mCRP
Monomeric C-reactive protein (mCRP) plays a role in cerebrovascular damage mediated by apolipoprotein E4 (ApoE4) in Alzheimer's disease (AD) pathogenesis. Using proteomic profilings, we found altered cytoskeleton proteins in the microvasculature of AD brains, including increased levels of hyperphosp...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-05-06 | PXD051529 | Pride
Apolipoprotein e (apoe)  monomeric c-reactive protein (mcrp)  lim domain and actin binding 1 (lima1)  cd31 and pcd31  cerebrovascular  endothelia  f-actin  alzheimer’s disease (ad) 
UnknownThe binding of monomeric C-reactive protein (mCRP) to Integrins αvβ3 and α4β1 is related to its pro-inflammatory action.
Not available
S-EPMC3973595 | biostudies-literature
UnknownMonomeric C-reactive protein and inflammation in age-related macular degeneration.
Not available
S-EPMC5527328 | biostudies-literature
UnknownAn Intrinsically Disordered Motif Mediates Diverse Actions of Monomeric C-reactive Protein.
Not available
S-EPMC4861447 | biostudies-literature
UnknownMonomeric C-reactive protein induces the cellular pathology of Alzheimer's disease.
Not available
S-EPMC9270638 | biostudies-literature
UnknownC-reactive protein (CRP) aptamer binds to monomeric but not pentameric form of CRP.
Not available
S-EPMC3538349 | biostudies-literature
UnknownPlasma Levels of Endothelial Microparticles Bearing Monomeric C-reactive Protein are Increased in Peripheral Artery Disease.
Not available
S-EPMC4874871 | biostudies-literature
UnknownOpposing effects of monomeric and pentameric C-reactive protein on endothelial progenitor cells.
Not available
S-EPMC3149664 | biostudies-literature
UnknownMonomeric C-reactive protein--a key molecule driving development of Alzheimer's disease associated with brain ischaemia?
Not available
S-EPMC4558604 | biostudies-literature
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