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Affinity based proteomic profiling is widely used for identification of proteins involved in for-mation of various interactomes. Pyruvate kinase (PK), a classical glycolytic enzyme catalyzing the last step of glycolysis, exists in four isoforms, one of which, PKM2; pyruvate kinase muscle isoform M2 ...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD041321 | Pride
Adaptive evolution of Pseudomonas putida in the presence of fluoride exposes moonlighting transporter functions
Emerging evidence indicates that metabolic enzymes perform moonlighting functions during tumor progression, including the modulation of chemoresistance. However, the underlying mechanisms of these functions remain elusive. In this study, utilizing a metabolic CRISPR-Cas9 knockout library screen, we ...
ORGANISM(S): Homo sapiens (Human) 
2024-11-15 | PXD055376 | Pride
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