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TranscriptomicsTranscription profiling of Drosophila infected with the parasitoid wasps Leptopilina boulardi and L. heterotoma to investigate infection strategies
Although host-parasitoid interactions are becoming well characterized at the organismal and cellular levels, much remains to be understood of the molecular bases for the host immune response and the parasitoids’ ability to defeat this immune response. Leptopilina boulardi and L. heterotoma, two c...
ORGANISM(S): Drosophila melanogaster 
2008-03-13 | E-GEOD-8938 | biostudies-arrayexpress
ProteomicsProject title Trypanosoma congolense s.l. natural infection induces proteome modifications in wild tsetse flies (Glossina palpalis palpalis)
Tsetse flies (Glossina spp.) are major vectors of African trypanosomes, causing either Human or Animal African Trypanosomiasis (HAT or AAT). Several approaches are developed to control the disease among which the anti-vector Sterile Insect Technique. Another approach in the frame of anti-vector stra...
ORGANISM(S): Trypanosoma brucei 
2023-07-26 | PXD034619 | Pride
Tsetse fly  trypanosomiasis  natural fly infection  differential protein expression  vector competence control. 
TranscriptomicsExpression profile of adult Drosophila melanogaster expressing a self-replicating RNA of Sindbis virus
Alphaviruses establish a persistent infection in arthropod vectors, which is essential for effective transmission of the virus to vertebrate hosts. The development of persistence in insects is not well understood, although it is thought to involve the innate immune response. Using a transgenic fly s...
ORGANISM(S): Drosophila melanogaster 
2013-01-31 | E-GEOD-42726 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of Drosophila melanogaster midgut during Pseudomonas entomophila infection
This study investigates transcriptional changes in the adult Drosophila melanogaster midgut upon oral infection with the entomopathogen Pseudomonas entomophila for 20 hours. Midgut samples were collected from 5–7 day old flies under two conditions: uninfected control and P. entomophila-infected. gen...
ORGANISM(S): Drosophila melanogaster 
2026-04-01 | E-MTAB-15668 | biostudies-arrayexpress
TranscriptomicsEndogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells
Small interfering RNAs (siRNAs) direct RNA interference (RNAi) in eukaryotes. In flies, somatic cells produce siRNAs from exogenous double-stranded RNA as a defense against viral infection. Here, we identify 21-nt long, endogenous siRNAs (endo-siRNAs) corresponding to transposons and heterochromatic...
ORGANISM(S): Drosophila melanogaster 
2008-04-10 | E-GEOD-11019 | biostudies-arrayexpress
TranscriptomicsThe effect of Wolbachia infection on Drosophila ovarian transcript levels
We used microarray analysis to screen the Drosophila genome for effects of Wolbachia infection on transcript levels in wildtype adult immature ovaries. Keywords: Comparative expression analysis of infection effect To generate the ovaries to be compared, we first rid a wildtype Canton-S line of Droso...
ORGANISM(S): Drosophila melanogaster 
2010-05-14 | E-GEOD-9274 | biostudies-arrayexpress
TranscriptomicsTracheal immune response to bacteria in Drosophila
Drosophila larvae were infected with Erwinia bacteria (Ecc15) by introducing concentrated bacterial pellet into the fly medium. The tracheae were dissected 24h later. Three genotypes of larvae were compared: wt (CantonS), RelE20 and PGRP-LA, each present in unchallenged and infected conditions. 3 in...
ORGANISM(S): Drosophila melanogaster 
2013-06-20 | E-MEXP-3925 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila mutant for transcription factors Dorsal, Dif, and Relish and their effect on immune response
The abstract of the manuscript titled "Microarray analyses reveal possible new targets for the Rel protein Dif in Drosophila melanogaster " is given below: ; The fruit fly Drosophila melanogaster express three closely related NF-κB-like transcription factors: Dorsal, Dif, and Relish. They share sig...
ORGANISM(S): Drosophila melanogaster 
2008-06-13 | E-GEOD-5489 | biostudies-arrayexpress
UnknownNatural infection of the sand fly Phlebotomus kazeruni by Trypanosoma species in Pakistan.
Not available
S-EPMC2845124 | biostudies-literature
TranscriptomicsThe small RNA profile in wildtype, R2D2 and loquacious mutant Drosophila
We used SOLiD technology to deep sequence libraries prepared from 18-35 nt PAGE purfied small RNAs derived from female Drosophila. The objective of our study was to compare the impact of R2D2 or loquacious mutantions on different small RNA populations in the fruit fly. We deep sequenced three separ...
ORGANISM(S): Drosophila melanogaster 
2009-11-04 | E-GEOD-18871 | biostudies-arrayexpress
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