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MetabolomicsGut Microbial Genes and Metabolism for Methionine and Branched-Chain Amino Acids in Diabetic Nephropathy

Diabetic mellitus nephropathy (DMN) is a serious complication of diabetes and a major health concern. Although the pathophysiology of diabetes mellitus (DM) leading to DMN is uncertain, recent evidence suggests the involvement of the gut microbiome. This study aimed to determine the relationships...

2023-03-01 | MTBLS6331 | MetaboLights
MetabolomicsMetabolomics of diabetic nephropathy
Not available
ORGANISM(S): Homo sapiens 
ST000691 | MetabolomicsWorkbench
MetabolomicsMetabolomics of immunoglobulin-producing cells in IgA nephropathy
Not available
ORGANISM(S): Homo sapiens 
ST000560 | MetabolomicsWorkbench
TranscriptomicsGene expression profiling in glomeruli from human kidneys with diabetic nephropathy
Gene expression profiling in glomeruli from human kidneys with diabetic nephropathy Keywords = Diabetes Keywords = kidney Keywords = glomeruli Keywords: other. This dataset is part of the TransQST collection.
ORGANISM(S): Homo sapiens 
2004-04-01 | E-GEOD-1009 | biostudies-arrayexpress
TranscriptomicsTranscriptomic and proteomic profiling reveal insights of mesangial cell function in patients with IgA Nephropathy
IgA nephropathy (IgAN) is the most common glomerulonephritis in the world. The disease is characterized by galactose deficient IgA (gd-IgA) in the circulation forming immune complexes. The complexes are deposited in the glomerular mesangium leading to inflammation and loss of renal function, but the...
ORGANISM(S): Homo sapiens 
2017-07-03 | E-GEOD-93798 | biostudies-arrayexpress
TranscriptomicsSystematic analysis of a human renal transcript dataset
Glomerular diseases account for the majority of cases with chronic renal failure. Several genes have been identified with key relevance for glomerular function. Quite a few of these genes show a specific or preferential mRNA expression in the renal glomerulus. To identify additional candidate genes ...
ORGANISM(S): Homo sapiens 
2010-07-19 | E-GEOD-21785 | biostudies-arrayexpress
MetabolomicsPlasma metabolomic profiling of diabetic nephropathy in the steptozotocin induced type-1 diabetes mouse model
Not available
ORGANISM(S): Mus musculus 
ST000558 | MetabolomicsWorkbench
ProteomicsProteomics in exploring the endothelial dysfunction mechanism induced by serum exosomes from diabetic retinopathy and diabetic nephropathy patients
In this study, we used human glomerular endothelial cells (HGECs) as cells model, proteomics TMT-based LC-MS/MS was employed to discover the underlying mechanisms of endothelial dysfunction caused by SExos from diabetic retinopathy and nephropathy patients.
ORGANISM(S): Homo Sapiens 
2021-12-29 | PXD030660 |
MetabolomicsKidney tissue metabolomic profiling of diabetic nephropathy in the steptozotocin induced type-1 diabetes mouse model.
Not available
ORGANISM(S): Mus musculus 
ST000540 | MetabolomicsWorkbench
GenomicsIgA Nephropathy GWAS (IGANGWAS)

We report a genome-wide association study of IgA nephropathy, a main cause of kidney failure. All subjects were of Chinese Han ancestry, of which 1,194 were cases and 902 controls. Genomic DNA samples extracted from whole blood were genotyped on the Illumina 610 Quad platform.

phs000431.v1.p1 | EGA
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