ocular surface - OmicsDI

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CHEBI ID

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Metabolite Name

Methionine (3)
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1,3-dipyridin-3-ylpropane-1,3-dione (1)
PE (18:0/18:1) (1)
PC (16:0/17:1) (1)
13,14-Dihydro prostaglandin E1 (1)
3'-O-Methylcytidine (1)
D-3-Phenyllactic acid (1)

First Public Date

2026 (33)
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Study type

Transcription profiling by array (116)
RNA-seq of coding RNA (8)
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Release Date

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2022 (258)
2023 (249)
2025 (238)
2024 (199)
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2013 (52)
2014 (50)
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1999 (1)

Lab affiliation

Centre for Ocular Regeneration (CORE), Prof. Brien Holden Eye Research Centre (BHERC), L V Prasad Eye Institute, Hyderabad, Telangana, India (2)
LBPC-PPC, Montpellier University, IRMB CHU Montpellier, INM INSERM, Montpellier, Occitanie, France (2)
School of Optometry, The Hong Kong Polytechnic University (2)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 138648 Singapore, Singapore. Department of Pharmacy, National University of Singapore, 117543, Singapore, Singapore. (1)
Byers Eye Institute, Stanford University (1)
Center for Biotechnology & Genomic Medicine, Dept. of Population Health Sciences Medical College of Georgia at Augusta University (1)
Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta University, USA (1)
Deparment of Molecular and Cellular Biology University of Guelph Guelph, Ontario, Canada Department of Proteomics and Signal Transduction Max Planck Institute of Biochemistry Martinsried, Germany (1)
Department of Chemistry (1)
Department of Experimental and Translational Ophthalmology, University Medical Center, Johannes Gutenberg University, Mainz, Germany (1)
Functional Proteomics Medizinisches Proteom-Center Germany (1)
GlycoProteomics Laboratory Sao Paulo University (1)
Institut National de la Santé et de la Recherche Médicale INSERM UMRS 968, CNRS UMR 7210, Institut de la Vision, IHU ForeSight, Sorbonne Université UM80, 75012 Paris, France (1)
Institute for Neurosciences of Montpellier, Univ Montpellier, INSERM, Montpellier, France (1)
Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore (1)
Istituto di Cristallografia, Consiglio Nazionale delle Ricerche, Sede Secondaria di Catania, Via Paolo Gaifami 18, 95126 Catania, Italy (1)
Medizinisches Proteom-Center, Ruhr-University Bochum, Bochum, Germany (1)
Molecular and Cellular Biology Department, University of Guelph (1)
Montpellier Hospital (1)
Proteomics Platform CIC bioGUNE Bizkaia Tech. Par Build. 800 48160 Derio (Spain) (1)
Proteomics Service CIC bioGUNE Bizkaia Tech. Park Build. 800 Derio 48160 Spain (1)
School of Optometry, The Hong Kong Polytechnic University, Hong Kong (1)
Senior Principal Research Scientist, Head, Ocular Proteomics Platform Singapore Eye Research Institute Singapore (1)
University of Houston (1)
University of Houston, Houston, TX 77204, USA (1)
Yale University (1)

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Tear lipidomics profiling reveals inflammatory dry eye disease-associated lipid metabolic remodeling at the ocular surface

This study aimed to investigate whether inflammatory dry eye disease (DED) is accompanied by abnormal lipid metabolic remodeling at the ocular surface. Tear samples were collected from patients with DED and matched healthy controls. Lipidomics profiling was performed using LC–MS/MS with a standardiz...

2026-04-03 | MTBLS14218 | MetaboLights

Tear lipidomics profiling reveals ocular-surface lipid remodeling associated with organelle stress in a mouse model of inflammatory dry eye disease

This study aimed to determine whether dry eye disease (DED) is accompanied by ocular-surface lipid remodeling and whether such changes converge on organelle stress–associated pathways in a mouse model of inflammatory dry eye. Tear samples were collected from mice and analyzed by LC–MS/MS–based non-t...

2026-04-04 | MTBLS14217 | MetaboLights

Comparative Proteomics Reveals Prolonged Corneal Preservation Impaired Ocular Surface Immunity Accompanied with Fibrosis in Human Stroma

Cornea transplantation is a widely performed procedure globally. However, storing donor corneas for extended periods in Optisol-GS storage medium at 4 ℃ can lead to reduced endothelial cell viability, causing severe stromal edema and opacification. This negatively impacts transplantation success. Th...

ORGANISM(S): Homo Sapiens (human)

2024-09-29 | PXD045907 | JPOST Repository

Ocular surface microbiome in DAOSD

Ocular surface microbiome in dupilumab associated ocular surface disease

PRJEB57775 | ENA

TFOS Lifestyle: Impact of cosmetics on the ocular surface.

Not available

S-EPMC11246752 | biostudies-literature

Transcription profiling of mouse T cell response to ocular pigment epithelial cells - role of thrombospondin 1

Ocular pigment epithelium (PE) cells promote the generation of T regulators (PE-induced Treg cells). Moreover, T cells exposed to PE acquire the capacity to suppress the activation of bystander T cells via TGFbeta. Membrane-bound TGFbeta on iris PE cells interacts with TGFbeta receptors on T cells, ...

ORGANISM(S): Mus musculus

2008-06-13 | E-GEOD-5134 | biostudies-arrayexpress

Assessing the ocular surface microbiome in severe ocular surface diseases.

Not available

S-EPMC7905829 | biostudies-literature

Calcium-sensing receptor (CaSR) modulates ocular surface chloride transport and its inhibition promotes ocular surface hydration.

Not available

S-EPMC11887457 | biostudies-literature

Anterior segment optical coherence tomography angiography in the assessment of ocular surface lesions.

Not available

S-EPMC11583202 | biostudies-literature

TFOS lifestyle: Impact of societal challenges on the ocular surface.