organelle signaling

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CHEBI ID

CHEBI:16708 (3)
CHEBI:13389 (2)
CHEBI:136236 (2)
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CHEBI:140361 (2)
CHEBI:140362 (2)
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CHEBI:17622 (2)
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Metabolite Name

Adenine (4)
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Modelling Approach

Protein-protein interaction network (1)

Lab affiliation

Aging and Muscle Metabolism Lab, Department of Biomedical Sciences & Service of Endocrinology, Diabetes and Metabolism, Faculty of Biology and Medicine, Lausanne University Hospital and University of Lausanne, Bugnon 7, 1005 Lausanne, Switzerland (1)
Associate professer (1)
Beijing, You An Men Wai Xi Tou Tiao No.10 Capital Medical University, Beijing Laboratory of Oral Health (1)
Biotechnology and Cell Signaling (CNRS/Université de Strasbourg, UMR 7242), Ecole Supérieure de Biotechnologie de Strasbourg, 300 Boulevard Sébastien Brant, 67400 Illkirch, France. (1)
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Department of Medicine and General Cytometry Service-Nucleus, Cancer Research Centre (CSIC/USAL/IBSAL). Avda. Universidad de Coimbra, S/N, 37007 Salamanca, Spain. Phone: +34 923294811 Fax: +34 923294743 (1)
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Department of Molecular biology, medical biochemistry and pathology, Faculty of Medicine, Laval University, Quebec, QC, Canada (1)
Department of Ophthalmology and Visual Science, University of Michigan, Ann Arbor, MI, USA Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, USA (1)
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Heidelberg University Centre for molecular biology (ZMBH) Im Neuenheimer Feld 282 69120 Heidelberg Germany (1)
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IsPrivate

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fungi (1)

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57.021464 (1)

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IDH1 Mutations Induce Organelle Defects Via Dysregulated Phospholipids (FA_HILICZ)

Infiltrating gliomas are devastating and incurable tumors. Amongst all gliomas, those harboring an isocitrate dehydrogenase 1 mutation (IDHmut), acquire a different tumor biology and clinical manifestation than those that are IDHWT. Understanding the unique metabolic profile reprogrammed by IDH1 ...

2020-11-24 | MTBLS1967 | MetaboLights

IDH1 Mutations Induce Organelle Defects Via Dysregulated Phospholipids (CSHpos)

2020-11-24 | MTBLS1974 | MetaboLights

IDH1 Mutations Induce Organelle Defects Via Dysregulated Phospholipids (CSHNeg)

2020-11-24 | MTBLS1973 | MetaboLights

Tear lipidomics profiling reveals ocular-surface lipid remodeling associated with organelle stress in a mouse model of inflammatory dry eye disease

This study aimed to determine whether dry eye disease (DED) is accompanied by ocular-surface lipid remodeling and whether such changes converge on organelle stress–associated pathways in a mouse model of inflammatory dry eye. Tear samples were collected from mice and analyzed by LC–MS/MS–based non-t...

2026-04-04 | MTBLS14217 | MetaboLights

Nitrate-Sialin2 Axis Couples ER-Mitochondrial Calcium Signaling with Fatty Acid Metabolism to Drive White Adipose Browning

Nutrient cues shape adipose homeostasis; however, the mechanism by which inorganic signals engage organelle networks to drive white fat browning remains unclear. Here, we identify a nitrate-Sialin2 pathway that converts dietary nitrate into a spatially confined thermogenic program. Sialin2 localizes...

2026-05-17 | MTBLS14192 | MetaboLights

Lysosome Lipid Signaling from the Periphery to Neurons Regulates Longevity

Lysosomes are key cellular organelles that metabolize extra- and intra-cellular substrates. Alterations in lysosomal metabolism are implicated in aging-associated metabolic and neurodegenerative diseases. However, how lysosomal metabolism actively coordinates the metabolic and nervous systems to ...

2022-05-06 | MTBLS4654 | MetaboLights

Mitochondrial two-component signaling systems in Candida albicans

Two-component signal transduction pathways are one of the primary means by which microorganisms respond to environmental signals. These signaling cascades originated in prokaryotes and were inherited by eukaryotes via endosymbiotic lateral gene transfer from ancestral cyanobacteria. We report here t...

ORGANISM(S): Candida albicans

2013-07-02 | E-GEOD-45438 | biostudies-arrayexpress

Proteomics identifies organelle specific phosphorylation and reveals major subcellular reorganization in the progression of NAFLD

Obesity induced non-alcoholic fatty liver disease (NAFLD) is associated with the development of type 2 diabetes and constitutes a major health problem. A hallmark of the diseases is extensive lipid droplet (LD) formation and accumulation of toxic lipid species interfering with cellular signaling and...

ORGANISM(S): Mus musculus (Mouse)

2018-10-29 | PXD007653 | Pride

Cyclophilin D extramitochondrial signaling controls cell cycle progression and chemokine-directed cell motility.

Mitochondria control bioenergetics and cell fate decisions, but whether they also participate in extra-organelle signaling is not understood. Here, we show that interference with cyclophilin D (CypD), a mitochondrial matrix protein and apoptosis regulator, causes accelerated cell proliferation and ...

ORGANISM(S): Mus musculus

2013-03-08 | E-GEOD-41280 | biostudies-arrayexpress

Functional multi-organelle units control inflammatory lipid metabolism of macrophages

PRJNA986140 | ENA

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