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MetabolomicsTranslational repression of viral RNA mediates arbovirus persistence in mosquitoes

Persistent infection of mosquito vectors is essential for the transmission of arboviruses, yet how these viruses produce sufficient progeny without compromising host cell fitness remains unclear. Arbovirus genomes exhibit suboptimal codon usage for both human and mosquito hosts, raising questions...

2026-02-12 | MTBLS12760 | MetaboLights
MetabolomicsAbsence of tmRNA Increases the Persistence to Cefotaxime and the Intercellular Accumulation of Metabolite GlcNAc in Aeromonas veronii
Bacterial persisters are a small proportion of phenotypically heterogeneous variants with the transient capability to survive in high concentrations of antibiotics, causing recurrent infections in both human and aquatic animals. Transfer-messenger RNA (tmRNA), which was encoded by the ssrA ge...
2021-10-18 | MTBLS1182 | MetaboLights
MetabolomicsAbsence of tmRNA increases the persistence to cefotaxime by upregulating the metabolites GlcNAc in Aeromonas veronii

Bacterial persisters refer to a small proportion of phenotypically heterogeneous variants with transient capability for survival when exposing to high concentrations of antibiotic, which constitute the major cause for recurrent infections both in human and aquatic infections. In pathogenic bacter...

2020-01-10 | MTBLS1191 | MetaboLights
ProteomicsProteome dynamics in persisting and resuscitating bacterial cells
Bacterial persister cells become transiently tolerant to antibiotics by restraining their growth and metabolic activity. Detailed molecular characterization of bacterial persistence is hindered by low count of persisting cells and the need for their isolation. Here we used sustained addition of stab...
ORGANISM(S): Escherichia coli 
2021-07-30 | PXD018153 | Pride
Hipb Resuscitation Hipa Persistence Escherichia coli 
ModelsBianca2013 - Persistence analysis in a Kolmogorov-type model for cancer-immune system competition
Persistence analysis in a Kolmogorov-type model for cancer-immune system competition AIP Conference Proceedings 1558, 1797 (2013); https://doi.org/10.1063/1.4825874 C. Bianca Dipartimento di Scienze Matematiche, Politecnico di Torino, Torino, Italy F. Pappalardo Dipartimento di Scienza del Farmaco, ...
2024-09-02 | BIOMD0000000900 | BioModels
Immuno-oncology 
UnknownProteome Dynamics during Antibiotic Persistence and Resuscitation.
Not available
S-EPMC8407246 | biostudies-literature
GenomicsListeria Persistence
Listeria Persistence
PRJEB1355 | ENA
GenomicsListeria Persistence
Listeria Persistence
PRJEB1356 | ENA
GenomicsBacterial/Fungal Persistence Gene Identification Project
Bacterial/Fungal Persistence Gene Identification Project
PRJNA67953 | ENA
ProteomicsBacterial persistence - Bacterial persistence is an active σS stress response to metabolic flux limitation
Bacterial persistence, found in dormant and starved cells, is a health threat due to transient antibiotic tolerance. Harnessing a novel method for persister generation, we determined the proteome, metabolite levels and the physiology of E.coli persisters in and during entry into dormancy and starvat...
ORGANISM(S): Escherichia coli 
2016-09-27 | PXD001968 | Pride
Antibiotic resistance E. coli 
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