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MetabolomicsSimultaneously discovering the fate and biochemical effects of pharmaceuticals through untargeted metabolomics
Untargeted metabolomics is an established approach in toxicology for characterising endogenous metabolic responses to xenobiotic exposure. Detecting the xenobiotic and its biotransformation products as part of the metabolomics analysis provides an opportunity to simultaneously gain deep insights int...
2023-07-03 | MTBLS2746 | MetaboLights
MetabolomicsBioactive molecule(s) of gut bacteria of Crocodile (Crocodylus palustris) as potential pharmaceuticals
Not available
ORGANISM(S): Pseudomonas aeruginosa 
ST002447 | MetabolomicsWorkbench
ProteomicsProteomic analysis of E. coli K-12 LE392, P. putida KT2440 under exposure of six non-antibiotic pharmaceuticals
The goals of this study are to use SWATH-MS to detect bacterial proteomic profiles of E. coli K-12 LE392 with conjugative RP4 plasmid, P. putida KT2440, and their protein response under the exposure of six kinds of non-antibiotic pharmaceuticals, i.e., ibuprofen (ibu), naproxen (nap), gemfibrozil (g...
ORGANISM(S): Escherichia coli Pseudomonas putida KT2440 
2022-02-15 | PXD012642 | Pride
Non-antibiotic pharmaceuticals Swath-ms P. putida E. coli 
ProteomicsHepatic proteome analysis of Atlantic salmon (Salmo salar) after exposure to environmental concentrations of human pharmaceuticals
Pharmaceuticals are pseudo persistent aquatic pollutants with unknown effects at environmentally relevant concentrations. Atlantic salmon (Salmo salar) were exposed to Acetaminophen: 54.77 ± 34.67; Atenolol: 11.08 ± 7.98 and Carbamazepine: 7.85 ± 0.13 µg•L-1 for 5 days. After Acetaminophen treatment...
ORGANISM(S): Salmo sp. 
2014-11-18 | PXD001354 | Pride
Salmon liver  pharmaceuticals  environmental levels  lc-msms 
ProteomicsProteomic analysis of Acinetobacter baylyi ADP1 under exposure of non-antibiotic pharmaceuticals
The goals of this study are to use SWATH-MS to detect bacterial proteomic profiles of wild-type Acinetobacter baylyi ADP1, and its protein response under the exposure of non-antibiotic pharmaceuticals, including ibuprofen, naproxen, gemfibrozil, diclofenac, propanolol, and iopromide. The concentrati...
ORGANISM(S): Acinetobacter sp. 
2020-05-22 | PXD016798 | Pride
Bacteria Non-antibiotic pharmaceuticals Swath-ms Acinetobacter baylyi adp1 
GenomicsCP124 Bacterial enrichments tested with different pharmaceuticals
CP124 Bacterial enrichments tested with different pharmaceuticals
PRJEB17985 | ENA
ProteomicsProteomic analysis of the digestive gland of Mitylus galloprovincialis exposed to a mixture of three pharmaceuticals
Proteomics to decipher the cocktail effects of three pharmaceuticals (diclofenac, carbamazepine and venlafaxine) as a mixture on the digestive gland of male mussels Mytilus galloprovincialis.
ORGANISM(S): Mytilus galloprovincialis (Mediterranean mussel) 
2023-12-21 | PXD045957 | Pride
Multi-omics Mechanism of action Proteomics Data fusion Pharmaceuticals Ecotoxicology Bivalves Mixture effect 
TranscriptomicsAtlantic salmon liver transcriptome response to exposure to three human pharmaceuticals
The combination of increasing consumption rates and limited elimination under conventional waste water treatment practices of many pharmaceutical compounds has now led to their detection in aquatic environments. Three of the most frequently detected pharmaceuticals in the environment are Acetaminoph...
ORGANISM(S): Salmo salar 
2012-02-29 | E-TABM-1213 | biostudies-arrayexpress
TranscriptomicsResponse of Rhodospirillum rubrum S1H to three pharmaceuticals
The present study explores the potential of compound-specific gene-upregulation profiles in the ubiquitous purple nonsulfur bacterium Rhodospirillum rubrum S1H as biomarkers for exposure to surface water contaminants, i.e. high production-volume pharmaceuticals. Even though the pharmaceuticals [i.e....
ORGANISM(S): Rhodospirillum rubrum 
2013-08-23 | E-GEOD-23794 | biostudies-arrayexpress
GenomicsRx-TGx: Toxicogenomic Study Of Pharmaceuticals Using RNA-Seq
Rx-TGx: Toxicogenomic Study Of Pharmaceuticals Using RNA-Seq
PRJNA603075 | ENA
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