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The goal of this study was to contrast genome-wide gene expression profiles of cultured human trabecular meshwork (HTM) cells, to that of control and primary open angle glaucoma (POAG) HTM tissues. Total RNA from cultured HTM cells and HTM tissue dissected from control and POAG anterior segments fix...
ORGANISM(S): Homo sapiens 
This study compared genome-wide expression profiles of individuals with and without Primary Open-Angle Glaucoma (POAG). One POAG case (case #6 with two replicates #10 and #11) carried a Q368X myocilin mutation. This study compared the genome-wide expression in human trabecular meshwork tissue betwe...
ORGANISM(S): Homo sapiens 
This study compared genome-wide expression profiles of individuals with and without Primary Open-Angle Glaucoma (POAG). One POAG case (case #6 with two replicates #10 and #11) carried a Q368X myocilin mutation.
ORGANISM(S): Homo sapiens 
2013-08-31 | GSE27276 | GEO
Primary open angle glaucoma (POAG) is a progressive optic neuropathy, which is a major cause of worldwide visual impairment and blindness. Pathological hallmarks of the glaucomatous optic nerve head include retinal ganglion cell axon loss and extracellular matrix (ECM) remodeling of the lamina cribr...
ORGANISM(S): Homo sapiens 
Primary open angle glaucoma (POAG) presents as an irreversible optic neuropathy with corresponding visual field deficits and no other notable symptoms. The pathophysiology of POAG remains poorly understood. Through proteomic analysis of aqueous humour (AH) from POAG patients, we aim to identify chan...
ORGANISM(S): Homo sapiens (Human) 
2024-05-23 | PXD033153 | Pride
GLAUGEN-Methylation in POAG
GLAUGEN-Methylation in POAG
AH metabolites/zinc chelators associated with POAG identified by GC-MS-based metabolomic analysis. Methanol/chloroform extraction, derivatization - methoxylamine hydrochloride and of N,O-Bis(trimethylsilyl)trifluoroacetamide
ORGANISM(S): Human 
2024-01-30 | MSV000093951 | MassIVE
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