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TranscriptomicsGene expression signatures for human iPSC and ESC lines
In comprehensive glycome analysis with a high-density lectin microarray, we have previously shown that the recombinant N-terminal domain of the lectin BC2L-C from Burkholderia cenocepacia (rBC2LCN) binds exclusively to undifferentiated human induced pluripotent stem (iPS) cells and embryonic stem (E...
ORGANISM(S): Homo sapiens 
2015-10-28 | E-GEOD-42099 | biostudies-arrayexpress
TranscriptomicsSpatial regulation of the glycocalyx component Podocalyxin is a switch for pro-metastatic function
The sialomucin Podocalyxin (PODXL) is required for normal tissue development and apicobasal cell polarity by promoting lumen formation. Strikingly, high PODXL expression is also associated with metastasis and poor clinical outcome in multiple tumour types, such as prostate cancer. Utilising prostate...
ORGANISM(S): Homo sapiens 
2023-03-17 | E-MTAB-11793 | biostudies-arrayexpress
ProteomicsSpatial regulation of the glycocalyx component Podocalyxin is a switch for pro-metastatic function
The sialomucin Podocalyxin (PODXL) is required for normal tissue development and apicobasal cell polarity by promoting lumen formation. Remarkably, high PODXL expression is also associated with metastasis and poor clinical outcome in multiple tumour types, such as prostate cancer. We performed exten...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD032911 | Pride
Prostate cancer Iinteractome Invasion Podocalyxin 
GenomicsPodocalyxin governs the barrier function of human endometrial epithelium and critically regulates receptivity for embryo implantation
Podocalyxin governs the barrier function of human endometrial epithelium and critically regulates receptivity for embryo implantation
PRJNA623636 | ENA
TranscriptomicsPodocalyxin governs the barrier function of human endometrial epithelium and critically regulates receptivity for embryo implantation
Embryo implantation is a key step in establishing pregnancy and a major limiting factor in IVF. Implantation requires the endometrium, the inner lining of the uterus, to transform from a non-receptive to a receptive state, to allow embryos to attach to the surface and enter into the tissue. However,...
ORGANISM(S): Homo sapiens 
2021-04-01 | GSE148274 | GEO
UnknownUrinary podocalyxin is an early marker for podocyte injury in patients with diabetes: establishment of a highly sensitive ELISA to detect urinary podocalyxin.
Not available
S-EPMC3464371 | biostudies-literature
ProteomicsExosomes of p53 mutant H1299 cells
Proteome of exosomes purified from H1299-p53R273H (mutant) and H1299-p53-/- cells, which found the levels of Podocalyxin altered in p53-mutant cells.
ORGANISM(S): Homo sapiens (Human) 
2018-12-04 | PXD011241 | Pride
Human  h1299  cancer  podocalyxin  p53 
UnknownPosttranslational microtubule modification alters podocalyxin-trafficking in epithelial cells.
Not available
S-EPMC12497838 | biostudies-literature
TranscriptomicsGene expression profile of podocalyxin-like protein 1(PODXL) overexpressing and GFP overexpressing control embryonic stem cells
The transmembrane signals maintain the pluripotency of human pluripotent stem cells (hPSCs) are rarely investigated. A transmembrane glycoprotein, podocalyxin-like protein 1 (PODXL, also called podocalyxin like protein-1, PCLP1, Gp200/GCTM-2, MEP21, and Thrombomucin), aside from its well-known role ...
ORGANISM(S): Homo sapiens 
2019-12-01 | GSE127218 | GEO
ProteomicsDevelopment of a multiplexed LCMS assay for the quantitation of podocyte injury biomarkers nephrin, podocalyxin, and podocin in human urine
Targeted peptide immunoaffinity LCMS was conducted on clarified human urine using stable isotope labeled peptides for the absolute quantitation of nephrin, podocalyxin and podocin in samples from CKD patients and controls.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-03-28 | MSV000094428 | MassIVE
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