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Bacterial physiology in general and the bacterial response to the presence of nutrients and to external signals in particular is regulated at different levels, from mRNA synthesis to translational regulation and protein modification. However, there are not standardized parameters for defining post-t...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2018-11-13 | PXD009809 | Pride
Post-transcriptional regulons coordinate the expression of groups of genes in eukaryotic cells, yet relatively few have been characterised. Parasitic trypanosomatids are particularly good models for studies on such mechanisms because they exhibit almost exclusive polycistronic, and unregulated, tran...
ORGANISM(S): Trypanosoma brucei 
2019-11-13 | PXD012450 | Pride
This study represents the first attempt to characterize the RNA chaperone Hfq regulon in bacterial pathogen using an integrative omics approach. Gene expression profiles were analyzed by RNA-seq and protein amounts in cell-associated and cell-free fractions were determined by LC-MS/MS technique. Com...
ORGANISM(S): Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) 
2019-07-02 | PXD013953 | Pride
The LIN28B-IMP1 post-transcriptional regulon has opposing effects on oncogenic signaling in the intestine
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