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Genomics
Sheep cells overexpress GNAI2 and PPP1CA
PRJNA1090239 | ENA
UnknownNodularin-R Synergistically Enhances Abiraterone Against Castrate- Resistant Prostate Cancer via PPP1CA Inhibition.
Not available
S-EPMC11569623 | biostudies-literature
TranscriptomicsPPP1CA and RPSA dual inhibition suppresses castration resistance and bone metastasis for prostate cancer by disrupting AR-V7/RANKL signaling
Androgen is important in the formation, development and progress of prostate cancer, and deprivation of androgen, which is also named castration, is an effective way in prostate cancer therapies. For patients undergoing castration therapies, castration was gradually becoming ineffective in prostate ...
ORGANISM(S): Homo sapiens 
2026-03-12 | GSE317174 | GEO
OtherPPP1CA and RPSA dual inhibition suppresses castration resistance and bone metastasis for prostate cancer by disrupting AR-V7/RANKL signaling
Androgen is important in the formation, development and progress of prostate cancer, and deprivation of androgen, which is also named castration, is an effective way in prostate cancer therapies. For patients undergoing castration therapies, castration was gradually becoming ineffective in prostate ...
ORGANISM(S): Homo sapiens 
2026-03-15 | GSE319473 | GEO
UnknownS100A4 targets PPP1CA/IL-17 to inhibit the senescence of sheep endometrial epithelial cells.
Not available
S-EPMC11633043 | biostudies-literature
ProteomicsProteomic identification of GAP-binding proteins in colorectal cancer reveals PPP1CA as a direct target of microbial GABA-mediated metabolic rewiring
This dataset corresponds to the proteomic analysis presented in Figure 6A of the manuscript “Obesity-driven microbial GABA depletion promotes metabolic rewiring and colorectal cancer progression.” We performed Drug Affinity Responsive Target Stability (DARTS) and co-immunoprecipitation proteomics us...
ORGANISM(S): Homo sapiens (Human) 
2026-06-21 | PXD069744 | Pride
Gaba  gap  ppp1ca 
GenomicsPPP1CA and RPSA dual inhibition suppresses castration resistance and bone metastasis for prostate cancer by disrupting AR-V7/RANKL signaling
PPP1CA and RPSA dual inhibition suppresses castration resistance and bone metastasis for prostate cancer by disrupting AR-V7/RANKL signaling
PRJNA1423507 | ENA
GenomicsPPP1CA and RPSA dual inhibition suppresses castration resistance and bone metastasis for prostate cancer by disrupting AR-V7/RANKL signaling
PPP1CA and RPSA dual inhibition suppresses castration resistance and bone metastasis for prostate cancer by disrupting AR-V7/RANKL signaling
PRJNA1406219 | ENA
UnknownCircGPRC5A enhances colorectal cancer progress by stabilizing PPP1CA and inducing YAP dephosphorylation.
Not available
S-EPMC10698990 | biostudies-literature
UnknownLysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration.
Not available
S-EPMC10482945 | biostudies-literature
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