Sort   by:  
 Page size 
ProteomicsThe novel pre-rRNA detection workflow “Riboprobing” identified a hitherto undescribed aberrant pre-rRNA
Ribosomes translate mRNA into proteins and are essential for every living organism. In eukaryotes both ribosomal subunits are rapidly assembled in a strict hierarchical order, starting in the nucleolus with transcription of a common precursor ribosomal RNA (pre-rRNA). This pre-rRNA encodes three of ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-04-29 | PXD047506 | Pride
Aberrant pre-rrna Primer extension Ribosome biogenesis Reverse transcription Pre-rrna processing 
ProteomicsQuantitative phosphoproteomic analysis of DNA-PK substrates
We conducted a TMT based phosphoproteomic analysis to identify DNA-PK substrates.
ORGANISM(S): Homo Sapiens 
2023-01-15 | PXD039454 |
ProteomicsRECQ5 mediates pre-rRNA processing in nucleolus
explore the biological function of RECQ5 in nucleolus
ORGANISM(S): Homo Sapiens 
2024-11-19 | PXD058022 |
ProteomicsNuclear VCP-like 2 (NVL2)-associated complex
LC-MSMS analysis of NVL2-associated pre-60S complex. To obtain more insights into the molecular mechanism of this effects caused by the mutant NVL2 in pre-60S complexes,we searched for additional proteins that preferentially interact with the NVL2(E365Q/E682Q) in comparison with wild-type NVL2. Co-m...
ORGANISM(S): Homo Sapiens (human) 
2025-01-31 | PXD057741 | JPOST Repository
ProteomicsBMAL1 associates with NOP58 in the nucleolus and contributes to pre-rRNA processing
The transcription factor BMAL1 is a core element of the circadian clock that contributes to cyclic control of genes transcribed by RNA polymerase II. By using biochemical cellular fractionation and immunofluorescence analyses we reveal a previously uncharacterized nucleolar localization for BMAL1. W...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-25 | PXD018946 | Pride
Bmal1 interactome Nucleolus Circadian clock Ribosome biogenesis 
TranscriptomicsSIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing [CLIP-Seq]
SIRT7 is an NAD+-dependent protein deacetylase with important roles in ribosome biogenesis and cell proliferation. Previous studies have established that SIRT7 is associated with RNA polymerase I, interacts with pre-rRNA and promotes rRNA synthesis. Here we show that SIRT7 is also associated with sn...
ORGANISM(S): Homo sapiens 
2016-01-07 | E-GEOD-76578 | biostudies-arrayexpress
TranscriptomicsSnapshots of pre-rRNA structural flexibility reveal eukaryotic 40S assembly dynamics at nucleotide resolution
Ribosome assembly in eukaryotes involves the activity of hundreds of assembly factors that direct the hierarchical assembly of ribosomal proteins and numerous ribosomal RNA folding steps. However, detailed insights into the function of assembly factors and ribosomal RNA folding events are lacking. T...
ORGANISM(S): Saccharomyces cerevisiae 
2014-11-14 | E-GEOD-52878 | biostudies-arrayexpress
GenomicsPre-rRNA chromatin binding in mouse leptotene/zygotene spermatocytes
Pre-rRNA chromatin binding in mouse leptotene/zygotene spermatocytes
PRJNA1526096 | ENA
ProteomicsRbp95 binds 25S rRNA helix H95 and cooperates with the Npa1 complex during early pre-60S particle maturation
Eukaryotic ribosome synthesis involves more than 200 assembly factors, which promote ribosomal RNA (rRNA) processing, modification and folding, and assembly of ribosomal proteins. The formation and maturation of the earliest pre-60S particles requires structural remodeling by the Npa1 complex, but i...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-13 | PXD030106 | Pride
Ribosome assembly factor Yeast S. cerevisiae Tandem-affinity purification (tap) Npa1 Pre-60s particles Rbp95 
GenomicsPre-rRNA chromatin binding in mouse pachytene spermatocytes [ChIRP-seq]
Pre-rRNA chromatin binding in mouse pachytene spermatocytes [ChIRP-seq]
PRJNA1454784 | ENA
Sort   by:  
 Page size