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ProteomicsRbp95 binds 25S rRNA helix H95 and cooperates with the Npa1 complex during early pre-60S particle maturation
Eukaryotic ribosome synthesis involves more than 200 assembly factors, which promote ribosomal RNA (rRNA) processing, modification and folding, and assembly of ribosomal proteins. The formation and maturation of the earliest pre-60S particles requires structural remodeling by the Npa1 complex, but i...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-13 | PXD030106 | Pride
Ribosome assembly factor Yeast S. cerevisiae Tandem-affinity purification (tap) Npa1 Pre-60s particles Rbp95 
UnknownRbp95 binds to 25S rRNA helix H95 and cooperates with the Npa1 complex during early pre-60S particle maturation.
Not available
S-EPMC9508819 | biostudies-literature
GenomicsGenome wide mapping of RBP95-HTP binding sites in yeast by CRAC
Genome wide mapping of RBP95-HTP binding sites in yeast by CRAC
PRJNA783799 | ENA
OtherGenome wide mapping of RBP95-HTP binding sites in yeast by CRAC
We report the application of the Cross-Linking and cDNA (CRAC) technique to identify binding sites of RBP95, ribosome assembly factors, on RNAs in vivo. Once sequenced, Rnas associated have been aligned to the yeast genomes and enrichment of specific RNAs has been studied in more details. Specifical...
ORGANISM(S): Saccharomyces cerevisiae 
2022-08-23 | GSE189589 | GEO
TranscriptomicsmRNA-seq of HCT116 RNF40 knockdown cells upon TNF-alpha stimulation
This analysis identifies genes which are affected upon RNF40 knockdown cells and/or TNF-alpha stimulation
ORGANISM(S): Homo sapiens 
2018-10-22 | E-MTAB-7197 | biostudies-arrayexpress
TranscriptomicsmRNA-seq of HCC1954 siControl and siRNF40
The analysis of genes affected upon RNF40 knockdown in HCC1954 cells
ORGANISM(S): Homo sapiens 
2020-11-16 | E-MTAB-9234 | biostudies-arrayexpress
TranscriptomicsRegulation of gene expression by WAC/RNF20/RNF40 in HEK293A cells
WAC is a known positive regulator of (macro)autophagy. WAC also forms a complex with RNF20/RNF40 to promote H2B monoubiquitination and hence to affect transcriptional regulation. This study addresses whether the WAC/RNF20/RNF40 complex regulates autophagy through effects on gene expression. WAC, RNF...
ORGANISM(S): Homo sapiens 
2015-12-17 | E-GEOD-66475 | biostudies-arrayexpress
TranscriptomicsRNF20/RNF40 supports aggressive behavior in cervical cancer by regulating peroxisome-based anti-ferroptotic mechanism
Cervical cancer treatments sometimes prove ineffective, indicating a need for personalized therapies. The present study demonstrate a strong correlation between high levels of the RNF20/RNF40 protein complex and aggressive cervical cancer. Our transcriptome analyzes uncovered a previously unknown ro...
ORGANISM(S): Homo sapiens 
2025-03-09 | E-MTAB-13917 | biostudies-arrayexpress
TranscriptomicsH3K4me3 occupancy after Rnf20 and Rnf40 knockout in intestinal epithelial cells isolated from mice
Intestinal epithelial cells (IECs) were isolated from the colon of Villin-CreERT2, Rnf20-flox and Rnf40-flox mice two weeks upon the Tamoxifen-induced, intestinal knockout of Rnf20 and Rnf40. ChIP-seq for H3K4me3 was performed using snap-frozen IECs.
ORGANISM(S): Mus musculus 
2021-06-16 | E-MTAB-9409 | biostudies-arrayexpress
TranscriptomicsmRNA-seq of intestinal epithelial cells isolated from Rnf20 and Rnf40 knockout mice
Intestinal epithelial cells (IECs) were isolated from the colon of Villin-CreERT2, Rnf20-flox and Rnf40-flox mice two weeks upon the Tamoxifen-induced, intestinal knockout of Rnf20 and Rnf40. RNA was isolated from snap-frozen IECs to perform mRNA-seq.
ORGANISM(S): Mus musculus 
2021-06-16 | E-MTAB-9405 | biostudies-arrayexpress
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