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The mechanisms of action of common food preservatives are poorly understood. As there is a drive to develop alternative preservatives, understanding the mechanisms of action of current preservatives can inform development of novel food preservatives to ensure their efficacy. Here we used TraDIS-Xpre...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
25 ml of a modified basal salts medium (BSM; Hareland et al. 1975, J Bacteriol 121:272) supplemented with 0.05% casamino acids (Becton & Dickinson, Sparks, USA), 0.05 % yeast extract (Oxoid, Basingstoke, UK) and 0.4 % glucose (Fisher Scientific, Loughborough, UK) flasks were inoculated with 2 x ...
ORGANISM(S): Burkholderia lata 
Using TraDIS-Xpress to find the genes that affect susceptibility to common food preservatives
Genomics
Preservatives and mouse gut microbiome
Antimicrobials have been shown to select for changes in biofilm formation and multidrug susceptibility in common human pathogens. We investigated whether common food preservatives selected for these changes in the food pathogen Salmonella enterica serovar Typhimurium. Bacteria were exposed to four f...
ORGANISM(S): Salmonella enterica 
Genomics
Clostridium spec for detection of novel food preservatives
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