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ProteomicsMass spectrometry-based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways
Progressive supranuclear palsy (PSP) is a neurodegenerative disorder clinically characterized by progressive postural instability, supranuclear gaze palsy, parkinsonism, and cognitive decline caused by degeneration in specific areas of the brain including globus pallidus (GP), substantia nigra, and ...
ORGANISM(S): Homo sapiens (Human) 
2022-12-08 | PXD031648 | Pride
Globus pallidus Psp Proteomics Progressive supranuclear palsy Mass spectrometry Human brain tissue 
GenomicsA cerebrospinal fluid microRNA analysis of progressive supranuclear palsy.
A cerebrospinal fluid microRNA analysis of progressive supranuclear palsy.
PRJNA776755 | ENA
ProteomicsBiomarkers discovery for progressive supranuclear palsy from the human cerebrospinal fluid using mass spectrometry-based proteomics
Progressive supranuclear palsy (PSP) is a neurodegenerative parkinsonian disorder. This study using CSF samples of PSP patients is a follow-up study to discover biomarkers related to the previous PSP brain results. This study is the first-ever attempt at an in-depth global proteomic study using more...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD041417 | Pride
Cerebrospinal fluid Proteomics Progressive supranuclear palsy Mass spectrometry Biomarkers 
ProteomicsProgressive Supranuclear Palsy motor cortex
Progressive Supranuclear palsy (PSP) is a 4-repeat (4-R) tauopathy. We hypothesized that the molecular diversity of tau could explain the heterogeneity seen in PSP disease progression. To test this hypothesis, we performed an extensive biochemical characterisation of the high molecular weight tau sp...
ORGANISM(S): Homo sapiens (Human) 
2025-10-03 | PXD045736 | Pride
Brain Motor cortex Human 
Genomics4R-Tau Seeding Activity Reveals Molecular Subtypes in Progressive Supranuclear Palsy
4R-Tau Seeding Activity Reveals Molecular Subtypes in Progressive Supranuclear Palsy
PRJNA1289105 | ENA
GenomicsA cerebrospinal fluid microRNA analysis of progressive supranuclear palsy.
The cerebrospinal fluid miRNAs expression was markedly altered in the patients with progressive supranuclear palsy and controls.
ORGANISM(S): Homo sapiens 
2021-12-05 | GSE186921 | GEO
Unknown4R-tau seeding activity reveals molecular subtypes in progressive supranuclear palsy.
Not available
S-EPMC12847749 | biostudies-literature
UnknownPDQ-8: A Simplified and Effective Tool Measuring Life Quality in Progressive Supranuclear Palsy.
Not available
S-EPMC9912724 | biostudies-literature
UnknownRapid Cognitive Deterioration in Progressive Supranuclear Palsy: A 1-Year Follow-Up Study.
Not available
S-EPMC11998687 | biostudies-literature
ProteomicsDeep proteome profiling of human cerebrospinal fluid from patients diagnosed with Multiple System Atrophy, Parkinson’s Disease, Dementia with Lewy Bodies, Progressive Supranuclear Palsy, and from Controls
Human cerebrospinal fluid was collected from patients diagnosed with neurodegenerative diseases including multiple system atrophy (n=28), Parkinson’s disease (n=40), dementia with Lewy bodies (n=20), progressive supranuclear palsy (n=39) and from controls (n=17) in order to perform a comparative qua...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD026802 | Pride
Human Cerebrospinal fluid Q-exactive hf-x Parkinson’s disease Mass spectrometry Evosep Multiple system atrophy Progressive supranuclear palsy Proteome Dementia with lewy bodies 
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