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Psychrobacter sp. strain PSP genome sequencing and assembly
Pituitary adenomas cause significant endocrine and mass-related morbidity. Not much is known about mechanisms underlying pituitary tumor pathogenesis. We searched for a side population (SP) in pituitary tumor, representing cells with high efflux capacity and potentially enriching for cancer/tumor st...
ORGANISM(S): Homo sapiens 
A mild olfactory dysfunction has been observed in frontotemporal dementias (FTD). However, the underlying molecular mechanisms associated to this deficit are poorly understood. Here, we applied mass spectrometry-based quantitative proteomics to analyse pathological effects on the olfactory bulb (OB)...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD011446 | Pride
Investigation into PSP using proteomic techniques. Through the use of different human brain preps, the differences between those with Progressive supranuclear palsy and those without will be compared
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD048456 | Pride
Purpose: To explore the side population (SP) in pancreatic ductal adenocarcinoma (PDAC) for its gene expression profile and its association to cancer stem cells (CSC) and to evaluate the value of genes from its gene signature on patient survival. Experimental design: Side and main population (MP) c...
ORGANISM(S): Homo sapiens 
Autophagy enhancement ameliorates tau burden and neurofilament pathology in sporadic PSP-RS neurons
Distinct microRNA signatures define sporadic PSP-RS and PD in patient-derived midbrain organoids
Progressive supranuclear palsy (PSP) is a tauopathy that presents region-specific patterns of neurodegeneration, affecting cortical and subcortical areas with relative selectivity. Among these, the anterior cingulate cortex (ACC) is of particular interest due to its involvement in executive function...
ORGANISM(S): Homo sapiens (Human) 
2026-05-19 | PXD066064 | Pride
Progressive supranuclear palsy, Richardson’s syndrome subtype (PSP-RS), is a tauopathy marked by early axonal pathology and neurodegeneration. Modeling sporadic PSP-RS in human neurons remained a major challenge. Here, we generated midbrain dopaminergic (mDA) neurons from induced pluripotent stem ce...
ORGANISM(S): Homo sapiens 
2026-01-30 | GSE313924 | GEO
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