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To investigate the novel link between CP-AMPARs and excitability, we assessed global PV interneuron transcriptome changes with FICSR-seq (Fixation-Capture Single Cell RNA Recovery-seq) on forebrain PV interneurons. FACS-assisted PV interneuron bulk RNA-seq of PV-Cre;lsl-eGFP-GluA2 mice and PV-Cre;ls...
ORGANISM(S): Mus musculus 
2024-07-05 | GSE262872 | GEO
Mouse cortex PV interneuron transcriptome changes assessed with FACS-assisted bulk RNA-seq
Pro-cognitive restoration of PV interneuron plasticity in neurodevelopmental disorders
To identify candidate regulators of experience-dependent PV IN plasticity genes or “XPGs” in CA3/CA2 PV INs, we designed an in vivo functional screen in adult mice to isolate translated mRNAs from CA3/CA2 PV INs that receive increased mossy fiber inputs, a trigger for experience-dependent PV IN plas...
ORGANISM(S): Mus musculus 
2025-07-01 | GSE283741 | GEO
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