Sort   by:  
 Page size 
UnknownProfiling molecular factors associated with pyknosis and developmental arrest induced by an opioid receptor antagonist and dihydroartemisinin in Plasmodium falciparum.
Not available
S-EPMC5608265 | biostudies-literature
ProteomicsTcdB of Clostridioides difficile mediates necrosis in epithelial cells and is depend on RAS
A Clostridioides difficile infection (CDI) is the most common nosocomial infection worldwide. The main virulence factors are TcdA and TcdB, which inhibit small Rho-GTPases. Inhibition of small Rho-GTPases leads to the so-called cytopathic effect, a reorganization of the actin cytoskeleton, an impair...
ORGANISM(S): Homo sapiens (Human) 
2022-05-19 | PXD031726 | Pride
Clostridioides difficile  c.diff.  tcdb  phosphoproteomics  ras  tcda  pyknosis  glucosyltransferase independent effect 
ProteomicsNigericin-Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis
Innate immune signaling relies on phosphorylation cascades for effective responses. While TLR4 stimulation has been well-studied, research on signaling after inflammasome triggers like nigericin is limited. We performed time-resolved phosphoproteomic profiling to explore kinase signaling downstream ...
ORGANISM(S): Homo sapiens (Human) 
2025-08-27 | PXD062943 | Pride
Innate immunity Signalling pathways Phosphoproteomics Pyroptosis Inflammasomes 
ProteomicsNigericin-Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis
Innate immune signaling relies on phosphorylation cascades for effective responses. While TLR4 stimulation has been well-studied, research on signaling after inflammasome triggers like nigericin is limited. We performed time-resolved phosphoproteomic profiling to explore kinase signaling downstream ...
ORGANISM(S): Homo sapiens (Human) 
2025-08-27 | PXD062818 | Pride
Innate immunity Signalling pathways Phosphoproteomics Pyroptosis Inflammasomes 
UnknownDeterioration of cognitive function after transient cerebral ischemia with amyloid-β infusion-possible amelioration of cognitive function by AT2 receptor activation.
Not available
S-EPMC7140348 | biostudies-literature
UnknownQuantitative Phosphoproteome Analysis of Clostridioides difficile Toxin B Treated Human Epithelial Cells.
Not available
S-EPMC6304397 | biostudies-literature
TranscriptomicsGeneration of human bronchial organoids for SARS-CoV-2 research
Coronavirus disease 2019 (COVID-19) is a disease that causes fatal disorders including severe pneumonia. To develop a therapeutic drug for COVID-19, a model that can reproduce the viral life cycle and can evaluate the drug efficacy of anti-viral drugs is essential. In this study, we established a me...
ORGANISM(S): Homo sapiens 
2020-05-26 | GSE150819 | GEO
UnknownWestern Zika Virus in Human Fetal Neural Progenitors Persists Long Term with Partial Cytopathic and Limited Immunogenic Effects.
Not available
S-EPMC5645151 | biostudies-literature
UnknownSynthesis, Crystal Structures, Antimicrobial Activity, and Acute Toxicity Evaluation of Chiral Zn(II) Schiff Base Complexes.
Not available
S-EPMC11643661 | biostudies-literature
UnknownEffect of uremic toxins on hippocampal cell damage: analysis in vitro and in rat model of chronic kidney disease.
Not available
S-EPMC7892929 | biostudies-literature
Sort   by:  
 Page size