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ProteomicsProteomics investigation of the time course responses of RAW264.7 macrophages to infections with the wild-type and twin-arginine translocation mutant strains of Brucella melitensis
Brucella, a notorious intracellular pathogen, causes chronic infections in many mammals, including humans. The twin-arginine translocation (Tat) pathway transports folded proteins across the cytoplasmic membrane; protein substrates translocated by Brucella include ABC transporters, oxidoreductases, ...
ORGANISM(S): Mus musculus (Mouse) 
2021-07-05 | PXD024658 | Pride
Brucella melitensis  twin-arginine protein translocation  immune response  raw264.7 cell model 
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of the murine macrophage cell line RAW264.7 Transcriptomes
Next Generation Sequencing Facilitates Quantitative Analysis of the murine macrophage cell line RAW264.7 Transcriptomes
PRJNA1261877 | ENA
ProteomicsTargeting Saa expression via siRNA mitigates preterm birth induced by maternal inflammation
Introduction: Placental inflammation is a major contributor to preterm birth (PTB), and there are currently few targeted strategies to prevent PTB and its associated adverse neonatal outcomes. Serum amyloid A (SAA), particularly the isoforms SAA1 and SAA2, are well-recognized inflammatory markers, b...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-12 | PXD072875 | Pride
P2x7r-dependent signaling Raw264.7 cell line Saa2 Sirna-mediated targeting of saa2 
TranscriptomicsTranscription profiling of mouse bone marrow-derived dendritic cells (BMDC), with cells that had been cocultured (1:5, tumor:BMDC) with mouse ovarian surface epithelial cell line (1D8) cells, with irradiated (50Gy) 1D8 cells, or with the supernatent from 1D8 cells (25%, v/v)
The Suppressor of cytokine signaling (SOCS) family of negative regulatory proteins are upregulated in response to several cytokines and pathogen-associated molecular patterns (PAMPs), and suppress cellular signaling responses by binding receptor phosphotyrosine residues. Exposure of bone marrow-deri...
ORGANISM(S): Mus musculus 
2009-02-28 | E-GEOD-10741 | biostudies-arrayexpress
TranscriptomicsLXR activation in RAW264.7 mouse macrophages expressing LXRalpha.
To identify novel LXR target genes, we conducted transcriptional profiling studies using RAW264.7 cells ectopically expressing LXRalpha Total RNA was isolated from RAW264.7 macrophages ectopically expressing LXRalpha as described in Venkateswaran et al. (2000); PNAS 97, 12097-12102. Cells were cult...
ORGANISM(S): Mus musculus 
2009-08-01 | E-GEOD-17088 | biostudies-arrayexpress
UnknownCell cytoskeleton and proliferation study for the RANKL-induced RAW264.7 differentiation.
Not available
S-EPMC8107080 | biostudies-literature
GenomicsThe Transcriptome of MHV or PVM Infected RAW264.7 Cell
The Transcriptome of MHV or PVM Infected RAW264.7 Cell
PRJNA1061783 | ENA
Unknown10-Gingerol Suppresses Osteoclastogenesis in RAW264.7 Cells and Zebrafish Osteoporotic Scales.
Not available
S-EPMC7978033 | biostudies-literature
GenomicsRAW264.7 macrophages lack Neuropeptide Y receptors, yet still respond to Neuropeptide Y stimuli
RAW264.7 macrophages lack Neuropeptide Y receptors, yet still respond to Neuropeptide Y stimuli
PRJNA1525210 | ENA
GenomicsDeoxynivalenol Induces Cell Senescence in RAW264.7 Macrophages via HIF-1α-Mediated Activation of the p53/p21 Pathway
DON induces cell senescence in RAW264.7 macrophages by modulating the HIF-1α/p53/p21 pathway
PRJEB73298 | ENA
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