Sort   by:  
 Page size 
ProteomicsTargeting Saa expression via siRNA mitigates preterm birth induced by maternal inflammation
Introduction: Placental inflammation is a major contributor to preterm birth (PTB), and there are currently few targeted strategies to prevent PTB and its associated adverse neonatal outcomes. Serum amyloid A (SAA), particularly the isoforms SAA1 and SAA2, are well-recognized inflammatory markers, b...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-12 | PXD072875 | Pride
P2x7r-dependent signaling Raw264.7 cell line Saa2 Sirna-mediated targeting of saa2 
UnknownMaternal siRNA silencing of placental SAA2 mitigates preterm birth following intrauterine inflammation.
Not available
S-EPMC9539923 | biostudies-literature
UnknownExpression of SAA1, SAA2 and SAA4 genes in human primary monocytes and monocyte-derived macrophages.
Not available
S-EPMC6524798 | biostudies-literature
UnknownIdentification and characterization of spontaneous AA amyloidosis in CD-1 mice used in toxicity studies: implications of SAA1 and SAA2 copy number variations.
Not available
S-EPMC11745502 | biostudies-literature
UnknownHuman serum amyloid A3 (SAA3) protein, expressed as a fusion protein with SAA2, binds the oxidized low density lipoprotein receptor.
Not available
S-EPMC4349446 | biostudies-literature
TranscriptomicsStromal Fibroblast Mutant Trp53 Promotes Mammary Tumor Development via Enhanced Secretion of Paracrine Factors
Mutations in the tumor suppressor gene TP53 have been identified in breast cancer-associated fibroblasts and are associated with poor patient prognosis. However, the functional impact of fibroblastic mutant p53 on breast cancer development remains unclear. To investigate this, we compared female mic...
ORGANISM(S): Mus musculus 
2025-12-05 | GSE296930 | GEO
TranscriptomicsSingle-cell RNA sequencing reveals B cell-related immunosuppressive landscape and a potential suppressor in hepatocellular carcinoma
Background Sophisticated tumor microenvironment is responsible for malignant progression and poor prognosis of hepatocellular carcinoma (HCC) patients. Discovering new therapeutic targets was desired for preferable treatments of HCC patients. Methods To uncover the HCC microenvironment, single-cell ...
ORGANISM(S): Homo sapiens 
2025-08-06 | GSE299340 | GEO
UnknownTargeting SAA expression via siRNA mitigates preterm birth induced by maternal inflammation.
Not available
S-EPMC12855142 | biostudies-literature
TranscriptomicsGene expression profiling of Stat3flx/flx/NIC breast tumors compared to wild type NIC tumors.
A Stat3-dependent transcription regulatory network involved in inflammation and metastasis is identified. Analyses of the gene expression data revealed that Stat3flx/flx/NIC tumors exhibited a significant reduction in the expression of factors involved in both tumor angiogenesis (fibronectin, von wi...
ORGANISM(S): Mus musculus 
2009-09-01 | GSE15632 | GEO
UnknownPrediction of influenza virus infection based on deep learning and peripheral blood proteomics: A diagnostic study.
Not available
S-EPMC12766177 | biostudies-literature
Sort   by:  
 Page size